Monofilament perforation subarachnoid hemorrhage rat model

Julian Cahill, John H. Zhang

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

The monofilament puncture model for the induction of a subarach-noid hemorrhage in the rat is a difficult procedure to master. It is, however, important to do so, not only for subarachnoid hemorrhage research but also for stroke models, as the procedure is very similar. The monofilament model is by far the best model for investigating subarachnoid hemorrhage. This model, although technically more difficult compared with other techniques, has become more popular of late as the injury created is more authentic. The following description will explain step by step how to master this procedure with ease. © 2009 Humana Press.
Original languageEnglish
Title of host publicationAnimal Models of Acute Neurological Injuries
PublisherHumana Totowa
Pages261-270
Number of pages10
ISBN (Electronic)978-1-60327-185-1
ISBN (Print)9781603271844, 978-1-61737-877-5
DOIs
StatePublished - Jan 1 2009

Publication series

NameSpringer Protocols Handbooks
ISSN (Print)1949-2448
ISSN (Electronic)1949-2456

ASJC Scopus Subject Areas

  • General Neuroscience
  • General Agricultural and Biological Sciences

Keywords

  • Monofilament puncture model
  • Subarachnoid hemorrhage
  • Vasospasm

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