Molecular hydrogen: A therapeutic antioxidant and beyond

Research output: Contribution to journalReview articlepeer-review

Abstract

Molecular hydrogen (H2 ) medicine research has flourished since a landmark publication in Nature Medicine that revealed the antioxidant and cytoprotective effects of hydrogen gas in a focal stroke model. Emerging evidence has consistently demonstrated that molecular hydrogen is a promising therapeutic option for a variety of diseases and the underlying comprehensive mechanisms is beyond pure hydroxyl radicals scavenging. The non-toxicity at high concentrations and rapid cellular diffusion features of molecular hydrogen ensure the feasibility and readiness of its clinical translation to human patients.

Original languageEnglish
Pages (from-to)219-222
Number of pages4
JournalMedical Gas Research
Volume6
Issue number4
DOIs
StatePublished - Oct 1 2016

ASJC Scopus Subject Areas

  • Neuroscience (miscellaneous)
  • Anesthesiology and Pain Medicine

Keywords

  • anti-apoptosis
  • anti-inflammation
  • biological effect
  • clinical application
  • free radical scavenger
  • hydrogen gas
  • hydrogen-oxygen nebulizer machine
  • hydrogen-saturated water/saline

Cite this