Modulation of melanosomal activity by cisplatin: Characterization of a novel cellular machinery that may evade chemosensitivity

Kevin G. Chen; Julio C. Valencia; Xing-Jie Liang; Werner Berens; Jill Paterson; Francois Rouzaud; Stephen Wincovitch; Susan H. Garfield; Vincent J. Hearing; Michael M. Gottesman

Modulation of melanosomal activity by cisplatin: Characterization of a novel cellular machinery that may evade chemosensitivity

Kevin G. Chen, Julio C. Valencia, Xing-Jie Liang, Werner Berens, Jill Paterson, Francois Rouzaud, Stephen Wincovitch, Susan H. Garfield, Vincent J. Hearing, Michael M. Gottesman

Research output: Contribution to journal › Article › peer-review

Original language	American English
Journal	Cancer Research
Volume	65
State	Published - May 1 2005
Externally published	Yes

Disciplines

Cell Biology
Biology

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@article{621cb3517df14802bd9e4f048ff81392,

title = "Modulation of melanosomal activity by cisplatin: Characterization of a novel cellular machinery that may evade chemosensitivity",

author = "Chen, \{Kevin G.\} and Valencia, \{Julio C.\} and Xing-Jie Liang and Werner Berens and Jill Paterson and Francois Rouzaud and Stephen Wincovitch and Garfield, \{Susan H.\} and Hearing, \{Vincent J.\} and Gottesman, \{Michael M.\}",

note = "Proc Amer Assoc Cancer Res, Volume 46, 2005 1487 Melanomas, derived from melanocytes, are intrinsically resistant to many chemotherapeutic agents including cisplatin. However, the potential role of melanogenesis in this intrinsic cisplatin resistance (ICR) in melanomas is unknown. In this study, we report an altered melanogenesis pathway that may be involved in ICR.",

year = "2005",

month = may,

day = "1",

language = "American English",

volume = "65",

journal = "Cancer Research",

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TY - JOUR

T1 - Modulation of melanosomal activity by cisplatin: Characterization of a novel cellular machinery that may evade chemosensitivity

AU - Chen, Kevin G.

AU - Valencia, Julio C.

AU - Liang, Xing-Jie

AU - Berens, Werner

AU - Paterson, Jill

AU - Rouzaud, Francois

AU - Wincovitch, Stephen

AU - Garfield, Susan H.

AU - Hearing, Vincent J.

AU - Gottesman, Michael M.

N1 - Proc Amer Assoc Cancer Res, Volume 46, 2005 1487 Melanomas, derived from melanocytes, are intrinsically resistant to many chemotherapeutic agents including cisplatin. However, the potential role of melanogenesis in this intrinsic cisplatin resistance (ICR) in melanomas is unknown. In this study, we report an altered melanogenesis pathway that may be involved in ICR.

PY - 2005/5/1

Y1 - 2005/5/1

UR - https://cancerres.aacrjournals.org/content/65/9_Supplement/348.4

M3 - Article

VL - 65

JO - Cancer Research

JF - Cancer Research

ER -

Modulation of melanosomal activity by cisplatin: Characterization of a novel cellular machinery that may evade chemosensitivity

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