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Mitochondrial survivin inhibits apoptosis and promotes tumorigenesis

  • Takehiko Dohi
  • , Elena Beltrami
  • , Nathan R. Wall
  • , Janet Plescia
  • , Dario C. Altieri

Research output: Contribution to journal › Article › peer-review

Original languageEnglish
Pages (from-to)1117-1127
Number of pages11
JournalJournal of Clinical Investigation
Volume114
Issue number8
DOIs
StatePublished - Oct 2004
Externally publishedYes

ASJC Scopus Subject Areas

  • General Medicine

Keywords

  • In Situ Nick-End Labeling
  • Recombinant Fusion Proteins/genetics
  • Neoplasms/metabolism
  • Inhibitor of Apoptosis Proteins
  • Humans
  • Subcellular Fractions/metabolism
  • Survivin
  • Staurosporine/pharmacology
  • Enzyme Inhibitors/pharmacology
  • Caspases/metabolism
  • Cell Hypoxia
  • Animals
  • Endopeptidase K/metabolism
  • Apoptosis/physiology
  • Neoplasm Proteins
  • Mitochondria/drug effects
  • Cell Line, Tumor
  • Enzyme Activation
  • HeLa Cells
  • Microtubule-Associated Proteins/metabolism

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