Microglia Autophagy Mediated by TMEM166 Promotes Ischemic Stroke Secondary to Carotid Artery Stenosis

Li Li, Paul R. Krafft, Na Zeng, Ranran Duan, Xiang Qi, Anwen Shao, Fushan Xue, John H. Zhang

Research output: Contribution to journalArticlepeer-review

Original languageEnglish
Pages (from-to)1416-1431
Number of pages16
JournalAging and Disease
Volume15
Issue number3
DOIs
StatePublished - Jun 1 2024

ASJC Scopus Subject Areas

  • Pathology and Forensic Medicine
  • Geriatrics and Gerontology
  • Clinical Neurology
  • Cell Biology

Keywords

  • Autophagy
  • TMEM166
  • carotid endarterectomy
  • microglia
  • stroke
  • Microglia/metabolism
  • Humans
  • Middle Aged
  • Membrane Proteins/genetics
  • Male
  • Endarterectomy, Carotid/adverse effects
  • Mice, Knockout
  • Animals
  • Ischemic Stroke/metabolism
  • Carotid Stenosis/genetics
  • Female
  • Mice
  • Aged
  • C-Reactive Protein/metabolism
  • TOR Serine-Threonine Kinases/metabolism
  • Disease Models, Animal

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