MeCP2 recognizes cytosine methylated tri-nucleotide and di-nucleotide sequences to tune transcription in the mammalian brain

Sabine Lagger, John C. Connelly, Gabriele Schweikert, Shaun Webb, Jim Selfridge, Bernard H. Ramsahoye, Miao Yu, Chuan He, Guido Sanguinetti, Lawrence C. Sowers, Malcolm D. Walkinshaw, Adrian Bird

Research output: Contribution to journalArticlepeer-review

Original languageEnglish
Article numbere1006793
JournalPLoS Genetics
Volume13
Issue number5
DOIs
StatePublished - May 2017
Externally publishedYes

ASJC Scopus Subject Areas

  • Ecology, Evolution, Behavior and Systematics
  • Molecular Biology
  • Genetics
  • Genetics(clinical)
  • Cancer Research

Keywords

  • Trinucleotide Repeats
  • Dinucleotide Repeats
  • Cytosine/metabolism
  • Epigenesis, Genetic
  • Mice, Inbred C57BL
  • Male
  • DNA Methylation
  • Animals
  • Methyl-CpG-Binding Protein 2/genetics
  • CpG Islands
  • Protein Binding
  • Mice
  • Rett Syndrome/genetics
  • Brain/metabolism

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