Maternal obesity increases DNA methylation and decreases RNA methylation in the human placenta

  • Wei Bin Shen
  • , Jingxiang Ni
  • , Ruofan Yao
  • , Katherine R. Goetzinger
  • , Christopher Harman
  • , E. Albert Reece
  • , Bingbing Wang
  • , Peixin Yang

Research output: Contribution to journalArticlepeer-review

Original languageEnglish
Pages (from-to)90-96
Number of pages7
JournalReproductive Toxicology
Volume107
DOIs
StatePublished - Jan 2022
Externally publishedYes

ASJC Scopus Subject Areas

  • Toxicology

Keywords

  • 5-Methylcytosine
  • Epigenetic
  • Maternal obesity
  • N6-Methyladenosine
  • Placenta
  • Humans
  • 5-Methylcytosine/metabolism
  • Placenta/metabolism
  • Pregnancy
  • DNA Methylation
  • RNA/metabolism
  • Adenosine/analogs & derivatives
  • Female
  • Methyltransferases/genetics
  • Pregnancy in Obesity/genetics

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