TY - JOUR
T1 - LPS-induced acute lung injury is attenuated by phosphodiesterase inhibition
T2 - Effects on proinflammatory mediators, metalloproteinases, NF-κB, and ICAM-1 expression
AU - Coimbra, Raul
AU - Melbostad, Heidi
AU - Loomis, William
AU - Porcides, Rafael D.
AU - Wolf, Paul
AU - Tobar, Maria
AU - Hoyt, David B.
PY - 2006/1
Y1 - 2006/1
KW - Acute lung injury
KW - Adhesion molecules
KW - Adult respiratory Distress syndrome
KW - Cytokines
KW - Endotoxemia
KW - Metalloproteinase
KW - Nuclear factor kappa B
KW - Pentoxifylline
KW - Phosphodiesterase inhibitor
KW - Sepsis
KW - Endotoxemia/chemically induced
KW - Intercellular Adhesion Molecule-1/metabolism
KW - Pentoxifylline/pharmacology
KW - Male
KW - Lipopolysaccharides
KW - Interleukin-8/metabolism
KW - Lung/drug effects
KW - Disease Models, Animal
KW - Matrix Metalloproteinase 2/metabolism
KW - Respiratory Distress Syndrome/etiology
KW - Matrix Metalloproteinase 9/metabolism
KW - Rats
KW - Rats, Sprague-Dawley
KW - Animals
KW - Peroxidase/metabolism
KW - NF-kappa B/metabolism
KW - Escherichia coli Infections/chemically induced
KW - Phosphodiesterase Inhibitors/pharmacology
UR - https://www.scopus.com/pages/publications/33646086502
UR - https://www.scopus.com/pages/publications/33646086502#tab=citedBy
UR - https://www.mendeley.com/catalogue/fd0603e7-ea70-3211-9abf-8c37436ba8fe/
U2 - 10.1097/01.ta.0000200075.12489.74
DO - 10.1097/01.ta.0000200075.12489.74
M3 - Article
C2 - 16456445
AN - SCOPUS:33646086502
SN - 0022-5282
VL - 60
SP - 115
EP - 125
JO - Journal of Trauma - Injury, Infection and Critical Care
JF - Journal of Trauma - Injury, Infection and Critical Care
IS - 1
ER -