Local Intraluminal Irrigation with Argatroban during Free Flap Repair in a Patient with Heparin-Induced Thrombocytopenia

David Macias; Daniel I. Kwon; Paul C. Walker; Nathaniel R. Peterson

doi:10.1177/0003489417693015

Local Intraluminal Irrigation with Argatroban during Free Flap Repair in a Patient with Heparin-Induced Thrombocytopenia

David Macias, Daniel I. Kwon, Paul C. Walker, Nathaniel R. Peterson

Research output: Contribution to journal › Article › peer-review

Abstract

Objective: This study describes a case of a successful free flap repair using argatroban for local intraluminal irrigation as a substitute to heparin in a patient with heparin-induced thrombocytopenia. Methods: Case report and review of literature. Results: The patient had an uneventful postoperative course, and the free flap survived without complications. Conclusions: The use of argatroban during microvascular surgery is likely to be safe and simple and may be effective in preventing micro-thrombotic complications during microvascular surgery, and it should be considered as an alternative to heparinized saline for local intraluminal irrigation.

Original language	English
Pages (from-to)	407-410
Number of pages	4
Journal	Annals of Otology, Rhinology and Laryngology
Volume	126
Issue number	5
DOIs	https://doi.org/10.1177/0003489417693015
State	Published - May 1 2017

ASJC Scopus Subject Areas

Otorhinolaryngology

Keywords

argatroban
free flap reconstruction
head and neck cancer
head and neck reconstruction
head and neck surgery
heparin-induced thrombocytopenia
microsurgery
radial forearm free flap

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AU - Walker, Paul C.

AU - Peterson, Nathaniel R.

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Local Intraluminal Irrigation with Argatroban during Free Flap Repair in a Patient with Heparin-Induced Thrombocytopenia

Abstract

ASJC Scopus Subject Areas

Keywords

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