LJ529 attenuates mast cell-related inflammation via A3R-PKCε-ALDH2 pathway after subarachnoid hemorrhage in rats

Tongyu Zhang; Lei Huang; Jianhua Peng; John H. Zhang; Hongqi Zhang

doi:10.1016/j.expneurol.2021.113686

LJ529 attenuates mast cell-related inflammation via A₃R-PKCε-ALDH2 pathway after subarachnoid hemorrhage in rats

Tongyu Zhang, Lei Huang, Jianhua Peng, John H. Zhang, Hongqi Zhang

Physiology Division

Research output: Contribution to journal › Article › peer-review

Original language	English
Article number	113686
Journal	Experimental Neurology
Volume	340
DOIs	https://doi.org/10.1016/j.expneurol.2021.113686
State	Published - Jun 2021

ASJC Scopus Subject Areas

Neurology
Developmental Neuroscience

Keywords

Adenosine A3 receptor
Inflammation
LJ529
Mast cells
Subarachnoid hemorrhage
Thionucleosides/pharmacology
Inflammation/metabolism
Rats
Receptor, Adenosine A3/biosynthesis
Male
Rats, Sprague-Dawley
Signal Transduction/drug effects
Dose-Response Relationship, Drug
Adenosine/analogs & derivatives
Animals
Protein Kinase C-epsilon/biosynthesis
Aldehyde Dehydrogenase, Mitochondrial/biosynthesis
Mast Cells/drug effects
Adenosine A3 Receptor Agonists/pharmacology
Subarachnoid Hemorrhage/drug therapy

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10.1016/j.expneurol.2021.113686

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Cite this

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title = "LJ529 attenuates mast cell-related inflammation via A3R-PKCε-ALDH2 pathway after subarachnoid hemorrhage in rats",

keywords = "Adenosine A3 receptor, Inflammation, LJ529, Mast cells, Subarachnoid hemorrhage, Thionucleosides/pharmacology, Inflammation/metabolism, Rats, Receptor, Adenosine A3/biosynthesis, Male, Rats, Sprague-Dawley, Signal Transduction/drug effects, Dose-Response Relationship, Drug, Adenosine/analogs & derivatives, Animals, Protein Kinase C-epsilon/biosynthesis, Aldehyde Dehydrogenase, Mitochondrial/biosynthesis, Mast Cells/drug effects, Adenosine A3 Receptor Agonists/pharmacology, Subarachnoid Hemorrhage/drug therapy",

author = "Tongyu Zhang and Lei Huang and Jianhua Peng and Zhang, {John H.} and Hongqi Zhang",

note = "Publisher Copyright: {\textcopyright} 2021",

year = "2021",

month = jun,

doi = "10.1016/j.expneurol.2021.113686",

language = "English",

volume = "340",

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T1 - LJ529 attenuates mast cell-related inflammation via A3R-PKCε-ALDH2 pathway after subarachnoid hemorrhage in rats

AU - Zhang, Tongyu

AU - Huang, Lei

AU - Peng, Jianhua

AU - Zhang, John H.

AU - Zhang, Hongqi

PY - 2021/6

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KW - Thionucleosides/pharmacology

KW - Inflammation/metabolism

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KW - Rats, Sprague-Dawley

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KW - Dose-Response Relationship, Drug

KW - Adenosine/analogs & derivatives

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KW - Protein Kinase C-epsilon/biosynthesis

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