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Intravitreal toxicology and duration of efficacy of a novel antiviral lipid prodrug of ganciclovir in liposome formulation

  • Lingyun Cheng
  • , Karl Y. Hostetler
  • , Sunan Chaidhawangul
  • , Michael F. Gardner
  • , James R. Beadle
  • , Kelly S. Keefe
  • , Germaine Bergeron-Lynn
  • , Gregory M. Severson
  • , Kelly A. Soules
  • , Arthur J. Mueller
  • , William R. Freeman

Research output: Contribution to journalArticlepeer-review

Original languageEnglish
Pages (from-to)1523-1532
Number of pages10
JournalInvestigative Ophthalmology and Visual Science
Volume41
Issue number6
StatePublished - May 2000
Externally publishedYes

ASJC Scopus Subject Areas

  • Ophthalmology
  • Sensory Systems
  • Cellular and Molecular Neuroscience

Keywords

  • Electroretinography
  • Herpes Simplex/pathology
  • Rabbits
  • Cytomegalovirus/drug effects
  • Antigens, Viral/analysis
  • Fibroblasts/cytology
  • Cells, Cultured
  • Ophthalmoscopy
  • Lung/cytology
  • Prodrugs/administration & dosage
  • Drug Carriers
  • Injections
  • Animals
  • Vitreous Body/drug effects
  • Eye Infections, Viral/pathology
  • Retinitis/pathology
  • Antiviral Agents/administration & dosage
  • Ganciclovir/administration & dosage
  • Liposomes
  • Drug Evaluation, Preclinical
  • Herpesvirus 1, Human/drug effects

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