@inbook{4212061d9fae4f5f8035ce02668b39ba,
title = "Intracerebral hemorrhage in mice",
abstract = "Intracerebral hemorrhage is the most devastating stroke subtype with high rates of mortality and morbidity. Furthermore, no clinically approved treatment exists that effectively increases survival or improves quality of life for survivors. Effective modeling is necessary to elucidate the pathophysiological mechanisms of intracerebral hemorrhage and evaluate potential therapeutic approaches. Rodent models are most utilized because of their cost-effectiveness, and because rodent brain development and structures are well documented. Herein, we describe two intracerebral hemorrhage mouse models: the autologous blood double-injection and collagenase infusion models.",
keywords = "Animal model, Autologous blood, Collagenase, Intracerebral hemorrhage, Mouse, Stroke, Collagenases/adverse effects, Animals, Cerebral Hemorrhage/chemically induced, Humans, Mice, Disease Models, Animal",
author = "Damon Klebe and Loretta Iniaghe and Sherrefa Burchell and Cesar Reis and Onat Akyol and Jiping Tang and Zhang, \{John H.\}",
note = "Publisher Copyright: {\textcopyright} 2018, Springer Science+Business Media, LLC.",
year = "2018",
month = feb,
day = "22",
doi = "10.1007/978-1-4939-7526-6\_7",
language = "English",
isbn = "978-1-4939-7524-2",
series = "Methods in Molecular Biology",
publisher = "Humana Press Inc.",
pages = "83--91",
booktitle = "Traumatic and Ischemic Injury",
}