Interleukin-37 suppresses the osteogenic responses of human aortic valve interstitial cells in vitro and alleviates valve lesions in mice

Qingchun Zeng; Rui Song; David A. Fullerton; Lihua Ao; Yufeng Zhai; Suzhao Li; Dov B. Ballak; Joseph C. Cleveland; T. Brett Reece; Timothy A. McKinsey; Dingli Xu; Charles A. Dinarello; Xianzhong Meng

doi:10.1073/pnas.1619667114

Interleukin-37 suppresses the osteogenic responses of human aortic valve interstitial cells in vitro and alleviates valve lesions in mice

Qingchun Zeng, Rui Song, David A. Fullerton, Lihua Ao, Yufeng Zhai, Suzhao Li, Dov B. Ballak, Joseph C. Cleveland, T. Brett Reece, Timothy A. McKinsey, Dingli Xu, Charles A. Dinarello, Xianzhong Meng

Physiology Division

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	1631-1636
Number of pages	6
Journal	Proceedings of the National Academy of Sciences of the United States of America
Volume	114
Issue number	7
DOIs	https://doi.org/10.1073/pnas.1619667114
State	Published - Feb 14 2017

ASJC Scopus Subject Areas

General

Keywords

Calcification
Inflammation
Oxidized low-density lipoprotein
Signal transduction
Toll-like receptors

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10.1073/pnas.1619667114

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Zeng, Q., Song, R., Fullerton, D. A., Ao, L., Zhai, Y., Li, S., Ballak, D. B., Cleveland, J. C., Reece, T. B., McKinsey, T. A., Xu, D., Dinarello, C. A., & Meng, X. (2017). Interleukin-37 suppresses the osteogenic responses of human aortic valve interstitial cells in vitro and alleviates valve lesions in mice. Proceedings of the National Academy of Sciences of the United States of America, 114(7), 1631-1636. https://doi.org/10.1073/pnas.1619667114

Interleukin-37 suppresses the osteogenic responses of human aortic valve interstitial cells in vitro and alleviates valve lesions in mice. / Zeng, Qingchun; Song, Rui; Fullerton, David A. et al.
In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 114, No. 7, 14.02.2017, p. 1631-1636.

Research output: Contribution to journal › Article › peer-review

Zeng, Q, Song, R, Fullerton, DA, Ao, L, Zhai, Y, Li, S, Ballak, DB, Cleveland, JC, Reece, TB, McKinsey, TA, Xu, D, Dinarello, CA & Meng, X 2017, 'Interleukin-37 suppresses the osteogenic responses of human aortic valve interstitial cells in vitro and alleviates valve lesions in mice', Proceedings of the National Academy of Sciences of the United States of America, vol. 114, no. 7, pp. 1631-1636. https://doi.org/10.1073/pnas.1619667114

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Interleukin-37 suppresses the osteogenic responses of human aortic valve interstitial cells in vitro and alleviates valve lesions in mice

ASJC Scopus Subject Areas

Keywords

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