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Interactions between GIPC-APPL and GIPC-TRP1 regulate melanosomal protein trafficking and melanogenesis in human melanocytes

  • Rajendra Kedlaya
  • , Gokul Kandala
  • , Tie Fu Liu
  • , Nityanand Maddodi
  • , Sulochana Devi
  • , Vijayasaradhi Setaluri

Research output: Contribution to journalArticlepeer-review

Original languageEnglish
Pages (from-to)227-233
Number of pages7
JournalArchives of Biochemistry and Biophysics
Volume508
Issue number2
DOIs
StatePublished - Apr 15 2011
Externally publishedYes

ASJC Scopus Subject Areas

  • Biophysics
  • Biochemistry
  • Molecular Biology

Keywords

  • Adaptor APPL
  • GIPC
  • Melanin pigmentation
  • Melanosomal proteins
  • PDZ proteins
  • Protein trafficking
  • Adaptor Proteins, Signal Transducing/deficiency
  • Humans
  • Signal Transduction/genetics
  • Phosphatidylinositol 3-Kinases/metabolism
  • Melanins/biosynthesis
  • Proto-Oncogene Proteins c-akt/metabolism
  • Trypsin/metabolism
  • Gene Knockdown Techniques
  • Protein Transport/genetics
  • Cell Line, Tumor
  • Protein Binding
  • Melanosomes/genetics

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