Integrated multimodal cell atlas of Alzheimer’s disease

Mariano I. Gabitto; Kyle J. Travaglini; Victoria M. Rachleff; Eitan S. Kaplan; Brian Long; Jeanelle Ariza; Yi Ding; Joseph T. Mahoney; Nick Dee; Jeff Goldy; Erica J. Melief; Anamika Agrawal; Omar Kana; Xingjian Zhen; Samuel T. Barlow; Krissy Brouner; Jazmin Campos; John Campos; Ambrose J. Carr; Tamara Casper; Rushil Chakrabarty; Michael Clark; Jonah Cool; Rachel Dalley; Martin Darvas; Song Lin Ding; Tim Dolbeare; Tom Egdorf; Luke Esposito; Rebecca Ferrer; Lynn E. Fleckenstein; Rohan Gala; Amanda Gary; Emily Gelfand; Jessica Gloe; Nathan Guilford; Junitta Guzman; Daniel Hirschstein; Windy Ho; Madison Hupp; Tim Jarsky; Nelson Johansen; Brian E. Kalmbach; Lisa M. Keene; Sarah Khawand; Mitchell D. Kilgore; Amanda Kirkland; Michael Kunst; Brian R. Lee; Mckaila Leytze; Christine L. Mac Donald; Jocelin Malone; Zoe Maltzer; Naomi Martin; Rachel McCue; Delissa McMillen; Gonzalo Mena; Emma Meyerdierks; Kelly P. Meyers; Tyler Mollenkopf; Mark Montine; Amber L. Nolan; Julie K. Nyhus; Paul A. Olsen; Maiya Pacleb; Chelsea M. Pagan; Nicholas Peña; Trangthanh Pham; Christina Alice Pom; Nadia Postupna; Christine Rimorin; Augustin Ruiz; Giuseppe A. Saldi; Aimee M. Schantz; Nadiya V. Shapovalova; Staci A. Sorensen; Brian Staats; Matt Sullivan; Susan M. Sunkin; Carol Thompson; Michael Tieu; Jonathan T. Ting; Amy Torkelson; Tracy Tran; Nasmil J. Valera Cuevas; Sarah Walling-Bell; Ming Qiang Wang; Jack Waters; Angela M. Wilson; Ming Xiao; David Haynor; Nicole M. Gatto; Suman Jayadev; Shoaib Mufti; Lydia Ng; Shubhabrata Mukherjee; Paul K. Crane; Caitlin S. Latimer; Boaz P. Levi; Kimberly A. Smith; Jennie L. Close; Jeremy A. Miller; Rebecca D. Hodge; Eric B. Larson; Thomas J. Grabowski; Michael Hawrylycz; C. Dirk Keene; Ed S. Lein

doi:10.1038/s41593-024-01774-5

Integrated multimodal cell atlas of Alzheimer’s disease

Mariano I. Gabitto
, Kyle J. Travaglini
, Victoria M. Rachleff
, Eitan S. Kaplan
, Brian Long
, Jeanelle Ariza
, Yi Ding
, Joseph T. Mahoney
, Nick Dee
, Jeff Goldy
, Erica J. Melief
, Anamika Agrawal
, Omar Kana
, Xingjian Zhen
, Samuel T. Barlow
, Krissy Brouner
, Jazmin Campos
, John Campos
, Ambrose J. Carr
, Tamara Casper

Rushil Chakrabarty, Michael Clark, Jonah Cool, Rachel Dalley, Martin Darvas, Song Lin Ding, Tim Dolbeare, Tom Egdorf, Luke Esposito, Rebecca Ferrer, Lynn E. Fleckenstein, Rohan Gala, Amanda Gary, Emily Gelfand, Jessica Gloe, Nathan Guilford, Junitta Guzman, Daniel Hirschstein, Windy Ho, Madison Hupp, Tim Jarsky, Nelson Johansen, Brian E. Kalmbach, Lisa M. Keene, Sarah Khawand, Mitchell D. Kilgore, Amanda Kirkland, Michael Kunst, Brian R. Lee, Mckaila Leytze, Christine L. Mac Donald, Jocelin Malone, Zoe Maltzer, Naomi Martin, Rachel McCue, Delissa McMillen, Gonzalo Mena, Emma Meyerdierks, Kelly P. Meyers, Tyler Mollenkopf, Mark Montine, Amber L. Nolan, Julie K. Nyhus, Paul A. Olsen, Maiya Pacleb, Chelsea M. Pagan, Nicholas Peña, Trangthanh Pham, Christina Alice Pom, Nadia Postupna, Christine Rimorin, Augustin Ruiz, Giuseppe A. Saldi, Aimee M. Schantz, Nadiya V. Shapovalova, Staci A. Sorensen, Brian Staats, Matt Sullivan, Susan M. Sunkin, Carol Thompson, Michael Tieu, Jonathan T. Ting, Amy Torkelson, Tracy Tran, Nasmil J. Valera Cuevas, Sarah Walling-Bell, Ming Qiang Wang, Jack Waters, Angela M. Wilson, Ming Xiao, David Haynor, Nicole M. Gatto, Suman Jayadev, Shoaib Mufti, Lydia Ng, Shubhabrata Mukherjee, Paul K. Crane, Caitlin S. Latimer, Boaz P. Levi, Kimberly A. Smith, Jennie L. Close, Jeremy A. Miller, Rebecca D. Hodge, Eric B. Larson, Thomas J. Grabowski, Michael Hawrylycz, C. Dirk Keene, Ed S. Lein

Research output: Contribution to journal › Article › peer-review

Original language	English
Article number	6129
Pages (from-to)	2366-2383
Number of pages	18
Journal	Nature Neuroscience
Volume	27
Issue number	12
DOIs	https://doi.org/10.1038/s41593-024-01774-5
State	Published - Dec 2024
Externally published	Yes

ASJC Scopus Subject Areas

General Neuroscience

Access to Document

10.1038/s41593-024-01774-5

OpenUrl availability

Full text

Cite this

Gabitto, M. I., Travaglini, K. J., Rachleff, V. M., Kaplan, E. S., Long, B., Ariza, J., Ding, Y., Mahoney, J. T., Dee, N., Goldy, J., Melief, E. J., Agrawal, A., Kana, O., Zhen, X., Barlow, S. T., Brouner, K., Campos, J., Campos, J., Carr, A. J., ... Lein, E. S. (2024). Integrated multimodal cell atlas of Alzheimer’s disease. Nature Neuroscience, 27(12), 2366-2383. Article 6129. https://doi.org/10.1038/s41593-024-01774-5

Gabitto, MI, Travaglini, KJ, Rachleff, VM, Kaplan, ES, Long, B, Ariza, J, Ding, Y, Mahoney, JT, Dee, N, Goldy, J, Melief, EJ, Agrawal, A, Kana, O, Zhen, X, Barlow, ST, Brouner, K, Campos, J, Campos, J, Carr, AJ, Casper, T, Chakrabarty, R, Clark, M, Cool, J, Dalley, R, Darvas, M, Ding, SL, Dolbeare, T, Egdorf, T, Esposito, L, Ferrer, R, Fleckenstein, LE, Gala, R, Gary, A, Gelfand, E, Gloe, J, Guilford, N, Guzman, J, Hirschstein, D, Ho, W, Hupp, M, Jarsky, T, Johansen, N, Kalmbach, BE, Keene, LM, Khawand, S, Kilgore, MD, Kirkland, A, Kunst, M, Lee, BR, Leytze, M, Mac Donald, CL, Malone, J, Maltzer, Z, Martin, N, McCue, R, McMillen, D, Mena, G, Meyerdierks, E, Meyers, KP, Mollenkopf, T, Montine, M, Nolan, AL, Nyhus, JK, Olsen, PA, Pacleb, M, Pagan, CM, Peña, N, Pham, T, Pom, CA, Postupna, N, Rimorin, C, Ruiz, A, Saldi, GA, Schantz, AM, Shapovalova, NV, Sorensen, SA, Staats, B, Sullivan, M, Sunkin, SM, Thompson, C, Tieu, M, Ting, JT, Torkelson, A, Tran, T, Valera Cuevas, NJ, Walling-Bell, S, Wang, MQ, Waters, J, Wilson, AM, Xiao, M, Haynor, D, Gatto, NM, Jayadev, S, Mufti, S, Ng, L, Mukherjee, S, Crane, PK, Latimer, CS, Levi, BP, Smith, KA, Close, JL, Miller, JA, Hodge, RD, Larson, EB, Grabowski, TJ, Hawrylycz, M, Keene, CD & Lein, ES 2024, 'Integrated multimodal cell atlas of Alzheimer’s disease', Nature Neuroscience, vol. 27, no. 12, 6129, pp. 2366-2383. https://doi.org/10.1038/s41593-024-01774-5

@article{319b3236b65e48bbb17035410830cbce,

title = "Integrated multimodal cell atlas of Alzheimer{\textquoteright}s disease",

author = "Gabitto, \{Mariano I.\} and Travaglini, \{Kyle J.\} and Rachleff, \{Victoria M.\} and Kaplan, \{Eitan S.\} and Brian Long and Jeanelle Ariza and Yi Ding and Mahoney, \{Joseph T.\} and Nick Dee and Jeff Goldy and Melief, \{Erica J.\} and Anamika Agrawal and Omar Kana and Xingjian Zhen and Barlow, \{Samuel T.\} and Krissy Brouner and Jazmin Campos and John Campos and Carr, \{Ambrose J.\} and Tamara Casper and Rushil Chakrabarty and Michael Clark and Jonah Cool and Rachel Dalley and Martin Darvas and Ding, \{Song Lin\} and Tim Dolbeare and Tom Egdorf and Luke Esposito and Rebecca Ferrer and Fleckenstein, \{Lynn E.\} and Rohan Gala and Amanda Gary and Emily Gelfand and Jessica Gloe and Nathan Guilford and Junitta Guzman and Daniel Hirschstein and Windy Ho and Madison Hupp and Tim Jarsky and Nelson Johansen and Kalmbach, \{Brian E.\} and Keene, \{Lisa M.\} and Sarah Khawand and Kilgore, \{Mitchell D.\} and Amanda Kirkland and Michael Kunst and Lee, \{Brian R.\} and Mckaila Leytze and \{Mac Donald\}, \{Christine L.\} and Jocelin Malone and Zoe Maltzer and Naomi Martin and Rachel McCue and Delissa McMillen and Gonzalo Mena and Emma Meyerdierks and Meyers, \{Kelly P.\} and Tyler Mollenkopf and Mark Montine and Nolan, \{Amber L.\} and Nyhus, \{Julie K.\} and Olsen, \{Paul A.\} and Maiya Pacleb and Pagan, \{Chelsea M.\} and Nicholas Pe{\~n}a and Trangthanh Pham and Pom, \{Christina Alice\} and Nadia Postupna and Christine Rimorin and Augustin Ruiz and Saldi, \{Giuseppe A.\} and Schantz, \{Aimee M.\} and Shapovalova, \{Nadiya V.\} and Sorensen, \{Staci A.\} and Brian Staats and Matt Sullivan and Sunkin, \{Susan M.\} and Carol Thompson and Michael Tieu and Ting, \{Jonathan T.\} and Amy Torkelson and Tracy Tran and \{Valera Cuevas\}, \{Nasmil J.\} and Sarah Walling-Bell and Wang, \{Ming Qiang\} and Jack Waters and Wilson, \{Angela M.\} and Ming Xiao and David Haynor and Gatto, \{Nicole M.\} and Suman Jayadev and Shoaib Mufti and Lydia Ng and Shubhabrata Mukherjee and Crane, \{Paul K.\} and Latimer, \{Caitlin S.\} and Levi, \{Boaz P.\} and Smith, \{Kimberly A.\} and Close, \{Jennie L.\} and Miller, \{Jeremy A.\} and Hodge, \{Rebecca D.\} and Larson, \{Eric B.\} and Grabowski, \{Thomas J.\} and Michael Hawrylycz and Keene, \{C. Dirk\} and Lein, \{Ed S.\}",

note = "Publisher Copyright: {\textcopyright} The Author(s) 2024.",

year = "2024",

month = dec,

doi = "10.1038/s41593-024-01774-5",

language = "English",

volume = "27",

pages = "2366--2383",

journal = "Nature Neuroscience",

issn = "1097-6256",

number = "12",

}

TY - JOUR

T1 - Integrated multimodal cell atlas of Alzheimer’s disease

AU - Gabitto, Mariano I.

AU - Travaglini, Kyle J.

AU - Rachleff, Victoria M.

AU - Kaplan, Eitan S.

AU - Long, Brian

AU - Ariza, Jeanelle

AU - Ding, Yi

AU - Mahoney, Joseph T.

AU - Dee, Nick

AU - Goldy, Jeff

AU - Melief, Erica J.

AU - Agrawal, Anamika

AU - Kana, Omar

AU - Zhen, Xingjian

AU - Barlow, Samuel T.

AU - Brouner, Krissy

AU - Campos, Jazmin

AU - Campos, John

AU - Carr, Ambrose J.

AU - Casper, Tamara

AU - Chakrabarty, Rushil

AU - Clark, Michael

AU - Cool, Jonah

AU - Dalley, Rachel

AU - Darvas, Martin

AU - Ding, Song Lin

AU - Dolbeare, Tim

AU - Egdorf, Tom

AU - Esposito, Luke

AU - Ferrer, Rebecca

AU - Fleckenstein, Lynn E.

AU - Gala, Rohan

AU - Gary, Amanda

AU - Gelfand, Emily

AU - Gloe, Jessica

AU - Guilford, Nathan

AU - Guzman, Junitta

AU - Hirschstein, Daniel

AU - Ho, Windy

AU - Hupp, Madison

AU - Jarsky, Tim

AU - Johansen, Nelson

AU - Kalmbach, Brian E.

AU - Keene, Lisa M.

AU - Khawand, Sarah

AU - Kilgore, Mitchell D.

AU - Kirkland, Amanda

AU - Kunst, Michael

AU - Lee, Brian R.

AU - Leytze, Mckaila

AU - Mac Donald, Christine L.

AU - Malone, Jocelin

AU - Maltzer, Zoe

AU - Martin, Naomi

AU - McCue, Rachel

AU - McMillen, Delissa

AU - Mena, Gonzalo

AU - Meyerdierks, Emma

AU - Meyers, Kelly P.

AU - Mollenkopf, Tyler

AU - Montine, Mark

AU - Nolan, Amber L.

AU - Nyhus, Julie K.

AU - Olsen, Paul A.

AU - Pacleb, Maiya

AU - Pagan, Chelsea M.

AU - Peña, Nicholas

AU - Pham, Trangthanh

AU - Pom, Christina Alice

AU - Postupna, Nadia

AU - Rimorin, Christine

AU - Ruiz, Augustin

AU - Saldi, Giuseppe A.

AU - Schantz, Aimee M.

AU - Shapovalova, Nadiya V.

AU - Sorensen, Staci A.

AU - Staats, Brian

AU - Sullivan, Matt

AU - Sunkin, Susan M.

AU - Thompson, Carol

AU - Tieu, Michael

AU - Ting, Jonathan T.

AU - Torkelson, Amy

AU - Tran, Tracy

AU - Valera Cuevas, Nasmil J.

AU - Walling-Bell, Sarah

AU - Wang, Ming Qiang

AU - Waters, Jack

AU - Wilson, Angela M.

AU - Xiao, Ming

AU - Haynor, David

AU - Gatto, Nicole M.

AU - Jayadev, Suman

AU - Mufti, Shoaib

AU - Ng, Lydia

AU - Mukherjee, Shubhabrata

AU - Crane, Paul K.

AU - Latimer, Caitlin S.

AU - Levi, Boaz P.

AU - Smith, Kimberly A.

AU - Close, Jennie L.

AU - Miller, Jeremy A.

AU - Hodge, Rebecca D.

AU - Larson, Eric B.

AU - Grabowski, Thomas J.

AU - Hawrylycz, Michael

AU - Keene, C. Dirk

AU - Lein, Ed S.

PY - 2024/12

Y1 - 2024/12

UR - https://www.scopus.com/pages/publications/85206804241

UR - https://www.scopus.com/pages/publications/85206804241#tab=citedBy

U2 - 10.1038/s41593-024-01774-5

DO - 10.1038/s41593-024-01774-5

M3 - Article

C2 - 39402379

AN - SCOPUS:85206804241

SN - 1097-6256

VL - 27

SP - 2366

EP - 2383

JO - Nature Neuroscience

JF - Nature Neuroscience

IS - 12

M1 - 6129

ER -

Integrated multimodal cell atlas of Alzheimer’s disease

ASJC Scopus Subject Areas

Access to Document

OpenUrl availability

Other files and links

Cite this