TY - JOUR
T1 - Insights into the regulation of TNF-α production in human mononuclear cells
T2 - The effects of non-specific phosphodiesterase inhibition
AU - Deree, Jessica
AU - Martins, Joilson O.
AU - Melbostad, Heidi
AU - Loomis, William H.
AU - Coimbra, Raul
PY - 2008/6
Y1 - 2008/6
KW - 5-monophosphate (cAMP)
KW - Cyclic adenosine-3
KW - Nuclear factor-κB (NF-κB)
KW - Pentoxifylline
KW - Sepsis
KW - cAMP-response element binding protein (CREB)
KW - Leukocytes, Mononuclear/drug effects
KW - Enzyme-Linked Immunosorbent Assay
KW - Sepsis/drug therapy
KW - Humans
KW - Pentoxifylline/pharmacology
KW - Tumor Necrosis Factor-alpha/biosynthesis
KW - Lipopolysaccharides/pharmacology
KW - Blotting, Western
KW - Electrophoretic Mobility Shift Assay
KW - NF-kappa B/drug effects
KW - Transcription, Genetic/drug effects
KW - Cyclic AMP Response Element-Binding Protein/drug effects
KW - Phosphodiesterase Inhibitors/pharmacology
KW - Phosphorylation/drug effects
UR - https://www.scopus.com/pages/publications/45749153058
UR - https://www.scopus.com/pages/publications/45749153058#tab=citedBy
U2 - 10.1590/S1807-59322008000300006
DO - 10.1590/S1807-59322008000300006
M3 - Article
C2 - 18568240
AN - SCOPUS:45749153058
SN - 1807-5932
VL - 63
SP - 321
EP - 328
JO - Clinics
JF - Clinics
IS - 3
ER -