Inhibition of PAR-2 Attenuates Neuroinflammation and Improves Short-Term Neurocognitive Functions Via ERK1/2 Signaling Following Asphyxia-Induced Cardiac Arrest in Rats

Umut Ocak, Pinar Eser Ocak, Lei Huang, Gang Zuo, Jun Yan, Xin Hu, Zhijun Song, John H. Zhang

Research output: Contribution to journalArticlepeer-review

Original languageEnglish
Pages (from-to)539-547
Number of pages9
JournalShock
Volume54
Issue number4
DOIs
StatePublished - Oct 1 2020

ASJC Scopus Subject Areas

  • Emergency Medicine
  • Critical Care and Intensive Care Medicine

Keywords

  • Cardiac arrest
  • global cerebral ischemia
  • neurocognitive
  • neuroinflammation
  • protease activated receptor 2
  • Rats
  • Male
  • Rats, Sprague-Dawley
  • Blotting, Western
  • Animals
  • MAP Kinase Signaling System/physiology
  • Receptor, PAR-2/genetics
  • Heart Arrest/metabolism
  • Asphyxia/metabolism

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