TY - JOUR
T1 - Inhibition of bone formation during space flight
AU - Morey, Emily R.
AU - Baylink, David J.
N1 - Parameters of bone formation and resorption were measured in rats orbited for 19.5 days aboard the Soviet Cosmos 782 biological satellite. The most striking effects were on bone formation. During flight, rats formed significantly less periosteal bone than did control rats on the ground.
PY - 1978
Y1 - 1978
N2 - Parameters of bone formation and resorption were measured in rats orbited for 19.5 days aboard the Soviet Cosmos 782 biological satellite. The most striking effects were on bone formation. During flight, rats formed significantly less periosteal bone than did control rats on the ground. An arrest line at both the periosteum and the endosteum of flight animals suggests that a complete cessation of bone growth occurred. During a 26-day postflight period, the defect in bone formation was corrected. No significant changes in bone resorption were observed.
AB - Parameters of bone formation and resorption were measured in rats orbited for 19.5 days aboard the Soviet Cosmos 782 biological satellite. The most striking effects were on bone formation. During flight, rats formed significantly less periosteal bone than did control rats on the ground. An arrest line at both the periosteum and the endosteum of flight animals suggests that a complete cessation of bone growth occurred. During a 26-day postflight period, the defect in bone formation was corrected. No significant changes in bone resorption were observed.
UR - https://www.scopus.com/pages/publications/0018076154
UR - https://www.scopus.com/pages/publications/0018076154#tab=citedBy
U2 - 10.1126/science.150643
DO - 10.1126/science.150643
M3 - Article
C2 - 150643
SN - 0036-8075
VL - 201
SP - 1138
EP - 1141
JO - Science
JF - Science
IS - 4361
ER -