TY - JOUR
T1 - Infratentorial Strokes for Posterior Circulation Folks
T2 - Clinical Correlations for Current Translational Therapeutics
AU - Lekic, Tim
AU - Krafft, Paul R.
AU - Coats, Jacqueline S.
AU - Obenaus, Andre
AU - Tang, Jiping
AU - Zhang, John H.
N1 - Funding Information:
Acknowledgments This review was partially supported by a grant from NIH NS53407 to John H. Zhang. The neuroimaging support was provided in part by a NASA cooperative agreement (NCCQ-XX) to Loma Linda University. The authors wish to thank Pete Hayes for assistance with animal imaging.
PY - 2011/6
Y1 - 2011/6
N2 - Approximately 20% of all strokes will occur in the infratentorial brain. This is within the vascular territory of the posterior vascular circulation. Very few clinical specifics are known about the therapeutic needs of this patient sub-population. Most evidence-based practices are founded from research about the treatment of anterior circulatory stroke. As a consequence, little is known about how stroke in the infratentorial brain region would require a different approach. We characterized the neurovascular features of infratentorial stroke, pathophysiological responses, and experimental models for further translational study. © 2011 Springer Science+Business Media, LLC.
AB - Approximately 20% of all strokes will occur in the infratentorial brain. This is within the vascular territory of the posterior vascular circulation. Very few clinical specifics are known about the therapeutic needs of this patient sub-population. Most evidence-based practices are founded from research about the treatment of anterior circulatory stroke. As a consequence, little is known about how stroke in the infratentorial brain region would require a different approach. We characterized the neurovascular features of infratentorial stroke, pathophysiological responses, and experimental models for further translational study. © 2011 Springer Science+Business Media, LLC.
KW - Experimental models
KW - Infratentorial
KW - Posterior circulation
KW - Stroke
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UR - https://www.mendeley.com/catalogue/ba9e963d-cc58-387c-8d7d-a16c471cf5d3/
U2 - 10.1007/s12975-011-0068-2
DO - 10.1007/s12975-011-0068-2
M3 - Review article
SN - 1868-4483
VL - 2
SP - 144
EP - 151
JO - Translational Stroke Research
JF - Translational Stroke Research
IS - 2
ER -