Immune Effector Cell Associated Neurotoxicity (ICANS) in Pediatric and Young Adult Patients Following Chimeric Antigen Receptor (CAR) T-Cell Therapy: Can We Optimize Early Diagnosis?

Brandon Douglas Brown; Francesco Paolo Tambaro; Mira Kohorst; Linda Chi; Kris Michael Mahadeo; Priti Tewari; Demetrios Petropoulos; John M. Slopis; Zsila Sadighi; Sajad Khazal

doi:10.3389/fonc.2021.634445

Immune Effector Cell Associated Neurotoxicity (ICANS) in Pediatric and Young Adult Patients Following Chimeric Antigen Receptor (CAR) T-Cell Therapy: Can We Optimize Early Diagnosis?

Brandon Douglas Brown
, Francesco Paolo Tambaro
, Mira Kohorst
, Linda Chi
, Kris Michael Mahadeo
, Priti Tewari
, Demetrios Petropoulos
, John M. Slopis
, Zsila Sadighi
, Sajad Khazal

Research output: Contribution to journal › Article › peer-review

Original language	English
Article number	634445
Journal	Frontiers in Oncology
Volume	11
DOIs	https://doi.org/10.3389/fonc.2021.634445
State	Published - Mar 8 2021
Externally published	Yes

ASJC Scopus Subject Areas

Oncology
Cancer Research

Keywords

Cornell Assessment for Pediatric Delirium
delirium
immune effector cell
immune effector cell neurotoxicity
immune effector cell-associated neurotoxicity

Access to Document

10.3389/fonc.2021.634445

OpenUrl availability

Full text

Cite this

Brown, B. D., Tambaro, F. P., Kohorst, M., Chi, L., Mahadeo, K. M., Tewari, P., Petropoulos, D., Slopis, J. M., Sadighi, Z., & Khazal, S. (2021). Immune Effector Cell Associated Neurotoxicity (ICANS) in Pediatric and Young Adult Patients Following Chimeric Antigen Receptor (CAR) T-Cell Therapy: Can We Optimize Early Diagnosis? Frontiers in Oncology, 11, Article 634445. https://doi.org/10.3389/fonc.2021.634445

Immune Effector Cell Associated Neurotoxicity (ICANS) in Pediatric and Young Adult Patients Following Chimeric Antigen Receptor (CAR) T-Cell Therapy: Can We Optimize Early Diagnosis? / Brown, Brandon Douglas; Tambaro, Francesco Paolo; Kohorst, Mira et al.
In: Frontiers in Oncology, Vol. 11, 634445, 08.03.2021.

Research output: Contribution to journal › Article › peer-review

Brown, BD, Tambaro, FP, Kohorst, M, Chi, L, Mahadeo, KM, Tewari, P, Petropoulos, D, Slopis, JM, Sadighi, Z & Khazal, S 2021, 'Immune Effector Cell Associated Neurotoxicity (ICANS) in Pediatric and Young Adult Patients Following Chimeric Antigen Receptor (CAR) T-Cell Therapy: Can We Optimize Early Diagnosis?', Frontiers in Oncology, vol. 11, 634445. https://doi.org/10.3389/fonc.2021.634445

@article{8956dd53b9c74ce28bb09aaa573523e8,

title = "Immune Effector Cell Associated Neurotoxicity (ICANS) in Pediatric and Young Adult Patients Following Chimeric Antigen Receptor (CAR) T-Cell Therapy: Can We Optimize Early Diagnosis?",

keywords = "Cornell Assessment for Pediatric Delirium, delirium, immune effector cell, immune effector cell neurotoxicity, immune effector cell-associated neurotoxicity",

author = "Brown, \{Brandon Douglas\} and Tambaro, \{Francesco Paolo\} and Mira Kohorst and Linda Chi and Mahadeo, \{Kris Michael\} and Priti Tewari and Demetrios Petropoulos and Slopis, \{John M.\} and Zsila Sadighi and Sajad Khazal",

note = "Copyright {\textcopyright} 2021 Brown, Tambaro, Kohorst, Chi, Mahadeo, Tewari, Petropoulos, Slopis, Sadighi and Khazal.",

year = "2021",

month = mar,

day = "8",

doi = "10.3389/fonc.2021.634445",

language = "English",

volume = "11",

journal = "Frontiers in Oncology",

issn = "2234-943X",

}

TY - JOUR

T1 - Immune Effector Cell Associated Neurotoxicity (ICANS) in Pediatric and Young Adult Patients Following Chimeric Antigen Receptor (CAR) T-Cell Therapy

T2 - Can We Optimize Early Diagnosis?

AU - Brown, Brandon Douglas

AU - Tambaro, Francesco Paolo

AU - Kohorst, Mira

AU - Chi, Linda

AU - Mahadeo, Kris Michael

AU - Tewari, Priti

AU - Petropoulos, Demetrios

AU - Slopis, John M.

AU - Sadighi, Zsila

AU - Khazal, Sajad

PY - 2021/3/8

Y1 - 2021/3/8

KW - Cornell Assessment for Pediatric Delirium

KW - delirium

KW - immune effector cell

KW - immune effector cell neurotoxicity

KW - immune effector cell-associated neurotoxicity

UR - https://www.scopus.com/pages/publications/85102937358

UR - https://www.scopus.com/pages/publications/85102937358#tab=citedBy

UR - https://www.mendeley.com/catalogue/35d72ae2-5223-3abe-be2a-7956ae06adec/

U2 - 10.3389/fonc.2021.634445

DO - 10.3389/fonc.2021.634445

M3 - Article

C2 - 33763368

AN - SCOPUS:85102937358

SN - 2234-943X

VL - 11

JO - Frontiers in Oncology

JF - Frontiers in Oncology

M1 - 634445

ER -

Immune Effector Cell Associated Neurotoxicity (ICANS) in Pediatric and Young Adult Patients Following Chimeric Antigen Receptor (CAR) T-Cell Therapy: Can We Optimize Early Diagnosis?

ASJC Scopus Subject Areas

Keywords

Access to Document

OpenUrl availability

Other files and links

Cite this