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Ikaros regulation of the BCL6/BACH2 axis and its clinical relevance in acute lymphoblastic leukemia

  • Zheng Ge
  • , Xilian Zhou
  • , Yan Gu
  • , Qi Han
  • , Jianyong Li
  • , Baoan Chen
  • , Qinyu Ge
  • , Elanora Dovat
  • , Jonathon L. Payne
  • , Tianyu Sun
  • , Chunhua Song
  • , Sinisa Dovat

Research output: Contribution to journalArticlepeer-review

Original languageEnglish
Pages (from-to)8022-8034
Number of pages13
JournalOncotarget
Volume8
Issue number5
DOIs
StatePublished - Jan 31 2017
Externally publishedYes

ASJC Scopus Subject Areas

  • Oncology

Keywords

  • Acute lymphoblastic leukemia
  • BACH2
  • BCL6
  • IKZF1
  • Proto-Oncogene Mas
  • Prognosis
  • Basic-Leucine Zipper Transcription Factors/genetics
  • Humans
  • Middle Aged
  • Male
  • Young Adult
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma/genetics
  • Transfection
  • Time Factors
  • Adult
  • Female
  • Binding Sites
  • Promoter Regions, Genetic
  • Casein Kinase II/antagonists & inhibitors
  • Signal Transduction
  • Kaplan-Meier Estimate
  • Gene Expression Regulation, Leukemic
  • Proto-Oncogene Proteins c-bcl-6/genetics
  • Tumor Suppressor Proteins/genetics
  • Ikaros Transcription Factor/genetics
  • Adolescent
  • Cell Line, Tumor
  • Aged
  • Protein Kinase Inhibitors/pharmacology

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