Identification of Selective Imidazopyridine CSF1R Inhibitors

John L. Kane; Gary Asmussen; Joseph Batchelor; Mandy Cromwell; Malika Fezoui; Maria Fitzgerald; Barret Giese; Tatiana Gladysheva; Stephanie Holley; Kelly Keefe; Michael Kothe; Becky Lam; Sungtaek Lim; Jinyu Liu; Liang Ma; Markus Metz; Andrew A. Scholte; Patrick Shum; Lin Li Wei; Lisa Woodworth; Andrea Edling

doi:10.1021/acsmedchemlett.4c00110

Identification of Selective Imidazopyridine CSF1R Inhibitors

John L. Kane
, Gary Asmussen
, Joseph Batchelor
, Mandy Cromwell
, Malika Fezoui
, Maria Fitzgerald
, Barret Giese
, Tatiana Gladysheva
, Stephanie Holley
, Kelly Keefe
, Michael Kothe
, Becky Lam
, Sungtaek Lim
, Jinyu Liu
, Liang Ma
, Markus Metz
, Andrew A. Scholte
, Patrick Shum
, Lin Li Wei
, Lisa Woodworth

Andrea Edling

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	722-730
Number of pages	9
Journal	ACS Medicinal Chemistry Letters
Volume	15
Issue number	5
DOIs	https://doi.org/10.1021/acsmedchemlett.4c00110
State	Published - May 9 2024
Externally published	Yes

ASJC Scopus Subject Areas

Biochemistry
Drug Discovery
Organic Chemistry

Keywords

Class III receptor tyrosine kinases
Colony stimulating factor-1
Imidazo[4,5-b]pyridine
Mononuclear phagocyte system

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10.1021/acsmedchemlett.4c00110

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Kane, J. L., Asmussen, G., Batchelor, J., Cromwell, M., Fezoui, M., Fitzgerald, M., Giese, B., Gladysheva, T., Holley, S., Keefe, K., Kothe, M., Lam, B., Lim, S., Liu, J., Ma, L., Metz, M., Scholte, A. A., Shum, P., Wei, L. L., ... Edling, A. (2024). Identification of Selective Imidazopyridine CSF1R Inhibitors. ACS Medicinal Chemistry Letters, 15(5), 722-730. https://doi.org/10.1021/acsmedchemlett.4c00110

Kane, JL, Asmussen, G, Batchelor, J, Cromwell, M, Fezoui, M, Fitzgerald, M, Giese, B, Gladysheva, T, Holley, S, Keefe, K, Kothe, M, Lam, B, Lim, S, Liu, J, Ma, L, Metz, M, Scholte, AA, Shum, P, Wei, LL, Woodworth, L & Edling, A 2024, 'Identification of Selective Imidazopyridine CSF1R Inhibitors', ACS Medicinal Chemistry Letters, vol. 15, no. 5, pp. 722-730. https://doi.org/10.1021/acsmedchemlett.4c00110

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AU - Fitzgerald, Maria

AU - Giese, Barret

AU - Gladysheva, Tatiana

AU - Holley, Stephanie

AU - Keefe, Kelly

AU - Kothe, Michael

AU - Lam, Becky

AU - Lim, Sungtaek

AU - Liu, Jinyu

AU - Ma, Liang

AU - Metz, Markus

AU - Scholte, Andrew A.

AU - Shum, Patrick

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AU - Edling, Andrea

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Identification of Selective Imidazopyridine CSF1R Inhibitors

ASJC Scopus Subject Areas

Keywords

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