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Hypertonic saline and pentoxifylline attenuates gut injury after hemorrhagic shock: The kinder, gentler resuscitation

  • Jessica Deree
  • , Tercio De Campos
  • , Edna Shenvi
  • , William H. Loomis
  • , David B. Hoyt
  • , Raul Coimbra

Research output: Contribution to journal › Article › peer-review

Original languageEnglish
Pages (from-to)818-827
Number of pages10
JournalJournal of Trauma - Injury, Infection and Critical Care
Volume62
Issue number4
DOIs
StatePublished - Apr 2007
Externally publishedYes

ASJC Scopus Subject Areas

  • Surgery
  • Critical Care and Intensive Care Medicine

Keywords

  • Hemorrhagic shock
  • Hypertonic saline
  • NF-κB
  • Nitric oxide
  • Pentoxifylline
  • Fluid Therapy
  • Ileum/metabolism
  • Phosphodiesterase Inhibitors/therapeutic use
  • Inflammation/prevention & control
  • Shock, Hemorrhagic/therapy
  • Male
  • Saline Solution, Hypertonic/therapeutic use
  • NF-kappa B/biosynthesis
  • Ringer's Lactate
  • Nitric Oxide Synthase/metabolism
  • Heme Oxygenase-1/biosynthesis
  • Down-Regulation
  • Rats
  • Abdominal Injuries/therapy
  • Rats, Sprague-Dawley
  • Animals
  • Isotonic Solutions
  • Pentoxifylline/therapeutic use
  • Cytokines/biosynthesis
  • Drug Combinations

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