Huperzine a provides neuroprotection against several cell death inducers using in vitro model systems of motor neuron cell death

Richelle A. Hemendinger; Edward J. Armstrong; Rafal Persinski; Julianne Todd; Jean Luc Mougeot; Franklin Volvovitz; Jeffrey Rosenfeld

doi:10.1007/BF03033367

Huperzine a provides neuroprotection against several cell death inducers using in vitro model systems of motor neuron cell death

Richelle A. Hemendinger
, Edward J. Armstrong
, Rafal Persinski
, Julianne Todd
, Jean Luc Mougeot
, Franklin Volvovitz
, Jeffrey Rosenfeld

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	49-61
Number of pages	13
Journal	Neurotoxicity Research
Volume	13
Issue number	1
DOIs	https://doi.org/10.1007/BF03033367
State	Published - Mar 2008
Externally published	Yes

Keywords

Alkaloids
Animals
Apoptosis/drug effects
Aspartic Acid/analogs & derivatives
Carbonyl Cyanide m-Chlorophenyl Hydrazone/toxicity
Cell Line
Drug Interactions
Enzyme Inhibitors/toxicity
Hydrogen Peroxide/toxicity
Ionophores/toxicity
Motor Neurons/cytology
Neuroprotective Agents/pharmacology
Organ Culture Techniques
Oxidants/toxicity
Rats
Rats, Sprague-Dawley
Sesquiterpenes/pharmacology
Spinal Cord/drug effects
Staurosporine/toxicity
Thapsigargin/toxicity

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@article{ff03a7afb06244ef8d3b168fe3b86c43,

title = "Huperzine a provides neuroprotection against several cell death inducers using in vitro model systems of motor neuron cell death",

keywords = "Alkaloids, Animals, Apoptosis/drug effects, Aspartic Acid/analogs \& derivatives, Carbonyl Cyanide m-Chlorophenyl Hydrazone/toxicity, Cell Line, Drug Interactions, Enzyme Inhibitors/toxicity, Hydrogen Peroxide/toxicity, Ionophores/toxicity, Motor Neurons/cytology, Neuroprotective Agents/pharmacology, Organ Culture Techniques, Oxidants/toxicity, Rats, Rats, Sprague-Dawley, Sesquiterpenes/pharmacology, Spinal Cord/drug effects, Staurosporine/toxicity, Thapsigargin/toxicity",

author = "Hemendinger, \{Richelle A.\} and Armstrong, \{Edward J.\} and Rafal Persinski and Julianne Todd and Mougeot, \{Jean Luc\} and Franklin Volvovitz and Jeffrey Rosenfeld",

note = "Funding Information: The authors gratefully thank Dr. Neil Cashman for providing the NSC34 cell line and Biomedisyn Corp. for providing the purified huperzine A. This work was supported by the Carolinas Healthcare Foundation.",

year = "2008",

month = mar,

doi = "10.1007/BF03033367",

language = "English",

volume = "13",

pages = "49--61",

journal = "Neurotoxicity Research",

issn = "1029-8428",

number = "1",

}

TY - JOUR

T1 - Huperzine a provides neuroprotection against several cell death inducers using in vitro model systems of motor neuron cell death

AU - Hemendinger, Richelle A.

AU - Armstrong, Edward J.

AU - Persinski, Rafal

AU - Todd, Julianne

AU - Mougeot, Jean Luc

AU - Volvovitz, Franklin

AU - Rosenfeld, Jeffrey

N1 - Funding Information: The authors gratefully thank Dr. Neil Cashman for providing the NSC34 cell line and Biomedisyn Corp. for providing the purified huperzine A. This work was supported by the Carolinas Healthcare Foundation.

PY - 2008/3

Y1 - 2008/3

KW - Alkaloids

KW - Animals

KW - Apoptosis/drug effects

KW - Aspartic Acid/analogs & derivatives

KW - Carbonyl Cyanide m-Chlorophenyl Hydrazone/toxicity

KW - Cell Line

KW - Drug Interactions

KW - Enzyme Inhibitors/toxicity

KW - Hydrogen Peroxide/toxicity

KW - Ionophores/toxicity

KW - Motor Neurons/cytology

KW - Neuroprotective Agents/pharmacology

KW - Organ Culture Techniques

KW - Oxidants/toxicity

KW - Rats

KW - Rats, Sprague-Dawley

KW - Sesquiterpenes/pharmacology

KW - Spinal Cord/drug effects

KW - Staurosporine/toxicity

KW - Thapsigargin/toxicity

UR - https://www.scopus.com/pages/publications/44649119542

UR - https://www.scopus.com/pages/publications/44649119542#tab=citedBy

U2 - 10.1007/BF03033367

DO - 10.1007/BF03033367

M3 - Article

C2 - 18367440

AN - SCOPUS:44649119542

SN - 1029-8428

VL - 13

SP - 49

EP - 61

JO - Neurotoxicity Research

JF - Neurotoxicity Research

IS - 1

ER -

Huperzine a provides neuroprotection against several cell death inducers using in vitro model systems of motor neuron cell death

Keywords

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