@article{c077ecd6ed774a9187df74370b1f6ac7,
title = "HEAT repeat 1 motif is required for B56γ-containing protein phosphatase 2A (B56γ-PP2A) holoenzyme assembly and tumor-suppressive function",
author = "Yumiko Nobumori and Shouse, {Geoffrey P.} and Li Fan and Xuan Liu",
note = "Background: How HEAT repeats contribute to PP2A assembly and function was unknown. Results: A tumor-associated mutation within HEAT repeat 1 disrupts PP2A function. Conclusion: HEAT repeat 1 is required for B56γ-PP2A assembly and tumor-suppressive function. Significance: This work provides structural insights into HEAT repeats and illuminates a mechanism to inactivate B56γ-PP2A.",
year = "2012",
month = mar,
day = "30",
doi = "10.1074/jbc.M111.334094",
language = "English",
volume = "287",
pages = "11030--11036",
journal = "Journal of Biological Chemistry",
issn = "0021-9258",
number = "14",
}