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Global expression profiling of peripheral Qa-1-restricted CD8αα+TCRαβ+ regulatory T cells reveals innate-like features: Implications for immune-regulatory repertoire

  • Shaohsuan S. Fanchiang
  • , Radu Cojocaru
  • , Mohammad Othman
  • , Ritu Khanna
  • , Matthew J. Brooks
  • , Trevor Smith
  • , Xiaolei Tang
  • , Igor Maricic
  • , Anand Swaroop
  • , Vipin Kumar

Research output: Contribution to journalArticlepeer-review

Original languageEnglish
Pages (from-to)214-222
Number of pages9
JournalHuman Immunology
Volume73
Issue number3
DOIs
StatePublished - Mar 2012
Externally publishedYes

ASJC Scopus Subject Areas

  • Immunology and Allergy
  • Immunology

Keywords

  • CD8 Treg
  • Experimental autoimmune encephalomyelitis
  • HLA-E
  • Innate cells
  • Microarray
  • Qa-1
  • CD8 + Treg
  • Killer Cells, Natural/immunology
  • Oligonucleotide Array Sequence Analysis
  • Receptors, Antigen, T-Cell, alpha-beta/genetics
  • Antigens, CD/metabolism
  • Humans
  • T-Lymphocytes, Regulatory/immunology
  • CD8 Antigens/metabolism
  • Gene Expression Profiling
  • Histocompatibility Antigens Class I/metabolism
  • Peripheral Tolerance
  • Clone Cells
  • Cell Line
  • Immunomodulation
  • Mice, Transgenic
  • Immunity, Innate
  • Animals
  • Protein Binding
  • Mice

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