Generation of integration/transgene-free stem cells

David J. Baylink; Kin-Hing W. Lau; Xiaobing Zhang

Generation of integration/transgene-free stem cells

David J. Baylink (Inventor)
, Kin-Hing W. Lau (Inventor)
, Xiaobing Zhang (Inventor)

Loma Linda University

Research output: Patent

Original language	American English
Patent number	WO2013177228A1
Filing date	5/21/13
State	Published - May 21 2013

Disciplines

Molecular Biology
Biology

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title = "Generation of integration/transgene-free stem cells",

author = "Baylink, \{David J.\} and Lau, \{Kin-Hing W.\} and Xiaobing Zhang",

note = "A vector for generating induced pluripotent stem cells from human target cells comprising a) a vector backbone, b) exactly two, three or four transcription and reprogramming factor genes, each gene separated by a 2a self-cleavage peptide sequence, c) a spleen focus-forming virus promoter, and d) a post-transcriptional regulatory element Wpre, with or without an anti-apoptotic factor gene.; WO2013177228A1",

year = "2013",

month = may,

day = "21",

language = "American English",

type = "Patent",

}

TY - PAT

T1 - Generation of integration/transgene-free stem cells

AU - Baylink, David J.

AU - Lau, Kin-Hing W.

AU - Zhang, Xiaobing

N1 - A vector for generating induced pluripotent stem cells from human target cells comprising a) a vector backbone, b) exactly two, three or four transcription and reprogramming factor genes, each gene separated by a 2a self-cleavage peptide sequence, c) a spleen focus-forming virus promoter, and d) a post-transcriptional regulatory element Wpre, with or without an anti-apoptotic factor gene.

PY - 2013/5/21

Y1 - 2013/5/21

UR - https://patents.google.com/patent/WO2013177228A1/en

M3 - Patent

M1 - WO2013177228A1

Y2 - 2013/05/21

ER -

Generation of integration/transgene-free stem cells

Disciplines

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