Fractalkine Enhances Hematoma Resolution and Improves Neurological Function via CX3CR1/AMPK/PPARγ Pathway After GMH

Xionghui Chen; Xuying He; Feng Xu; Ningbo Xu; Nona Hashem Sharifi; Pengjie Zhang; Jerry J. Flores; Lei Wu; Qiuguang He; Hideki Kanamaru; Shiyi Zhu; Siyuan Dong; Mingyang Han; Ye Yuan; Lei Huang; Liyan Miao; John H. Zhang; Youxin Zhou; Jiping Tang

doi:10.1161/STROKEAHA.123.043005

Fractalkine Enhances Hematoma Resolution and Improves Neurological Function via CX3CR1/AMPK/PPARγ Pathway After GMH

Xionghui Chen, Xuying He, Feng Xu, Ningbo Xu, Nona Hashem Sharifi, Pengjie Zhang, Jerry J. Flores, Lei Wu, Qiuguang He, Hideki Kanamaru, Shiyi Zhu, Siyuan Dong, Mingyang Han, Ye Yuan, Lei Huang, Liyan Miao, John H. Zhang, Youxin Zhou, Jiping Tang

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	2420-2433
Number of pages	14
Journal	Stroke
Volume	54
Issue number	9
DOIs	https://doi.org/10.1161/STROKEAHA.123.043005
State	Published - Sep 1 2023

ASJC Scopus Subject Areas

Clinical Neurology
Cardiology and Cardiovascular Medicine
Advanced and Specialized Nursing

Keywords

CX3C chemokine receptor 1
fractalkine
hematoma
hemorrhage
microglia
Microglia/metabolism
PPAR gamma/metabolism
Neuroinflammatory Diseases
CX3C Chemokine Receptor 1/metabolism
Humans
Infant, Newborn, Diseases
Rats
Chemokine CX3CL1/metabolism
Hematoma/metabolism
Rats, Sprague-Dawley
Animals
Cerebral Hemorrhage/drug therapy
AMP-Activated Protein Kinases/metabolism
Infant, Newborn

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10.1161/STROKEAHA.123.043005

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Chen, X., He, X., Xu, F., Xu, N., Sharifi, N. H., Zhang, P., Flores, J. J., Wu, L., He, Q., Kanamaru, H., Zhu, S., Dong, S., Han, M., Yuan, Y., Huang, L., Miao, L., Zhang, J. H., Zhou, Y., & Tang, J. (2023). Fractalkine Enhances Hematoma Resolution and Improves Neurological Function via CX3CR1/AMPK/PPARγ Pathway After GMH. Stroke, 54(9), 2420-2433. https://doi.org/10.1161/STROKEAHA.123.043005

Chen, X, He, X, Xu, F, Xu, N, Sharifi, NH, Zhang, P, Flores, JJ, Wu, L, He, Q, Kanamaru, H, Zhu, S, Dong, S, Han, M, Yuan, Y, Huang, L, Miao, L, Zhang, JH, Zhou, Y & Tang, J 2023, 'Fractalkine Enhances Hematoma Resolution and Improves Neurological Function via CX3CR1/AMPK/PPARγ Pathway After GMH', Stroke, vol. 54, no. 9, pp. 2420-2433. https://doi.org/10.1161/STROKEAHA.123.043005

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title = "Fractalkine Enhances Hematoma Resolution and Improves Neurological Function via CX3CR1/AMPK/PPARγ Pathway After GMH",

keywords = "CX3C chemokine receptor 1, fractalkine, hematoma, hemorrhage, microglia, Microglia/metabolism, PPAR gamma/metabolism, Neuroinflammatory Diseases, CX3C Chemokine Receptor 1/metabolism, Humans, Infant, Newborn, Diseases, Rats, Chemokine CX3CL1/metabolism, Hematoma/metabolism, Rats, Sprague-Dawley, Animals, Cerebral Hemorrhage/drug therapy, AMP-Activated Protein Kinases/metabolism, Infant, Newborn",

author = "Xionghui Chen and Xuying He and Feng Xu and Ningbo Xu and Sharifi, {Nona Hashem} and Pengjie Zhang and Flores, {Jerry J.} and Lei Wu and Qiuguang He and Hideki Kanamaru and Shiyi Zhu and Siyuan Dong and Mingyang Han and Ye Yuan and Lei Huang and Liyan Miao and Zhang, {John H.} and Youxin Zhou and Jiping Tang",

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AU - Chen, Xionghui

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AU - Xu, Feng

AU - Xu, Ningbo

AU - Sharifi, Nona Hashem

AU - Zhang, Pengjie

AU - Flores, Jerry J.

AU - Wu, Lei

AU - He, Qiuguang

AU - Kanamaru, Hideki

AU - Zhu, Shiyi

AU - Dong, Siyuan

AU - Han, Mingyang

AU - Yuan, Ye

AU - Huang, Lei

AU - Miao, Liyan

AU - Zhang, John H.

AU - Zhou, Youxin

AU - Tang, Jiping

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KW - hemorrhage

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KW - PPAR gamma/metabolism

KW - Neuroinflammatory Diseases

KW - CX3C Chemokine Receptor 1/metabolism

KW - Humans

KW - Infant, Newborn, Diseases

KW - Rats

KW - Chemokine CX3CL1/metabolism

KW - Hematoma/metabolism

KW - Rats, Sprague-Dawley

KW - Animals

KW - Cerebral Hemorrhage/drug therapy

KW - AMP-Activated Protein Kinases/metabolism

KW - Infant, Newborn

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Fractalkine Enhances Hematoma Resolution and Improves Neurological Function via CX3CR1/AMPK/PPARγ Pathway After GMH

ASJC Scopus Subject Areas

Keywords

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