Formaldehyde, aspartame, and migraines: a possible connection.

Sharon E. Jacob, Sarah Stechschulte

Research output: Contribution to journalArticlepeer-review

Abstract

Aspartame is a widely used artificial sweetener that has been linked to pediatric and adolescent migraines. Upon ingestion, aspartame is broken, converted, and oxidized into formaldehyde in various tissues. We present the first case series of aspartame-associated migraines related to clinically relevant positive reactions to formaldehyde on patch testing.

Original languageEnglish
Pages (from-to)E10-11
JournalDermatitis
Volume19
Issue number3
StatePublished - 2008

ASJC Scopus Subject Areas

  • Immunology and Allergy
  • Dermatology

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