First attempts at prediction of DNA strand-break yields using nanodosimetric data

G. Garty, R. Schulte, S. Shchemelinin, B. Grosswendt, C. Leloup, G. Assaf, A. Breskin, R. Chechik, V. Bashkirov

Research output: Contribution to journalArticlepeer-review

Abstract

We present the first results of our attempts to correlate yields of ionisation clusters in a gas model of DNA and corresponding double-strand break (DSB) yields in irradiated plasmids, using a simple statistical model of DNA lesion formation. Based on the same statistical model, we also provide a comparison of simulated nanodosimetric data for electrons and published DSB yields obtained with the PARTRAC code.

Original languageEnglish
Pages (from-to)451-454
Number of pages4
JournalRadiation Protection Dosimetry
Volume122
Issue number1-4
DOIs
StatePublished - Dec 2006

ASJC Scopus Subject Areas

  • Radiological and Ultrasound Technology
  • Radiation
  • Radiology Nuclear Medicine and imaging
  • Public Health, Environmental and Occupational Health

Cite this