Ex vivo isolation, expansion and bioengineering of CCR7+CD95-/or CD62L+CD45RA+ tumor infiltrating lymphocytes from acute myeloid leukemia patients’ bone marrow

Huynh Cao, Do Hyun Kim, Ashley Howard, Hector Moz, Samiksha Wasnik, David J. Baylink, Chien Shing Chen, Mark E. Reeves, Saied Mirshahidi, Jeffrey Xiao, Olivia Francis, Guido Marcucci, Yi Xu

Research output: Contribution to journalArticlepeer-review

Original languageEnglish
Pages (from-to)1252-1260
Number of pages9
JournalNeoplasia (United States)
Volume23
Issue number12
DOIs
StatePublished - Dec 2021

ASJC Scopus Subject Areas

  • Cancer Research

Keywords

  • Acute myeloid leukemia
  • Adoptive cell therapy
  • Bone marrow
  • CAR-T
  • CCR7
  • CD45RA
  • CD62L
  • CD95
  • Immunotherapy
  • Interleukin
  • Naïve T
  • PD-1
  • Programmed cell death protein 1
  • Tumor-Infiltrating Lymphocytes
  • Leukemia, Myeloid, Acute/immunology
  • Receptors, CCR7/immunology
  • Humans
  • Middle Aged
  • Male
  • fas Receptor/immunology
  • Leukocyte Common Antigens/immunology
  • Lymphocytes, Tumor-Infiltrating/immunology
  • Heterografts
  • T-Lymphocyte Subsets/immunology
  • Adult
  • Female
  • L-Selectin/immunology
  • Bioengineering/methods
  • Animals
  • Bone Marrow Cells/immunology
  • Aged
  • Cell Separation/methods
  • Mice
  • Adoptive Transfer/methods

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