TY - JOUR
T1 - Evaluation of Management of Community Acquired Pneumonia Prior to Implementation of an Antimicrobial Stewardship Program Initiative: A Retrospective Assessment
AU - Walsh, Thomas
AU - Disilvio, Briana
AU - Speredelozzi, Daniel
AU - Hammer, Crystal
AU - Hu, Kurt
AU - Abdulmassih, Rasha
AU - Makadia, Jina
AU - Sandhu, Rikinder
AU - Naddour, Mouhib
AU - Vishwanathan, Swati
AU - Chan-Tompkins, Noreen
AU - Trienski, Tamara
AU - Moffa, Matthew
AU - Bremmer, Derek
N1 - Conclusion: We were surprised to identify the treatment duration in our cohort was ≤ 7 days in only 26% of patients, while 38% received 10 days of therapy. Our findings are concerning given the available data demonstrating that short-course therapy with 5 - 7 days is clinically as effective as long-course therapy and associated with fewer adverse events.
PY - 2016/12/1
Y1 - 2016/12/1
N2 - Background. Community acquired pneumonia (CAP) remains a leading cause of hospitalization and mortality in the United States. Studies have shown that interventions such as shorter antibiotic therapy and early intravenous (IV) to oral conversion can be safely performed. We evaluated areas of improvement at our institutions that could help optimize patient management while reducing collateral damage associated with excessive antibiotic usage. Methods. In this retrospective analysis, all patients aged 18 years and older with a primary ICD-9 code for CAP admitted 1 March 2014 to 31 October 2014 were analyzed. The primary outcome was duration of antibiotic therapy for CAP (appropriate treatment duration defined as 5-7 days). Secondary objectives included duration of intravenous antibiotic therapy, duration of inpatient length of stay, and 30-day readmission rate related to CAP. Results. Of the 141 patients evaluated, 98 patients met inclusion criteria. The mean age was 63.8 (SD: 16.9 years). Chronic lung disease was present in 53 (54%) of patients, while 17 (17.4%) required use of supplemental oxygen at home. The primary and secondary outcomes can be seen in the table. Outcomes are presented as means; SD = standard deviation. Conclusion. We were surprised to identify the treatment duration in our cohort was 10 days of therapy. Our findings are concerning given the available data demonstrating that short-course therapy with 5-7 days is clinically as effective as long-course therapy and associated with fewer adverse events. The management of CAP represents a significant opportunity for antimicrobial stewardship intervention. (Table Presented) .
AB - Background. Community acquired pneumonia (CAP) remains a leading cause of hospitalization and mortality in the United States. Studies have shown that interventions such as shorter antibiotic therapy and early intravenous (IV) to oral conversion can be safely performed. We evaluated areas of improvement at our institutions that could help optimize patient management while reducing collateral damage associated with excessive antibiotic usage. Methods. In this retrospective analysis, all patients aged 18 years and older with a primary ICD-9 code for CAP admitted 1 March 2014 to 31 October 2014 were analyzed. The primary outcome was duration of antibiotic therapy for CAP (appropriate treatment duration defined as 5-7 days). Secondary objectives included duration of intravenous antibiotic therapy, duration of inpatient length of stay, and 30-day readmission rate related to CAP. Results. Of the 141 patients evaluated, 98 patients met inclusion criteria. The mean age was 63.8 (SD: 16.9 years). Chronic lung disease was present in 53 (54%) of patients, while 17 (17.4%) required use of supplemental oxygen at home. The primary and secondary outcomes can be seen in the table. Outcomes are presented as means; SD = standard deviation. Conclusion. We were surprised to identify the treatment duration in our cohort was 10 days of therapy. Our findings are concerning given the available data demonstrating that short-course therapy with 5-7 days is clinically as effective as long-course therapy and associated with fewer adverse events. The management of CAP represents a significant opportunity for antimicrobial stewardship intervention. (Table Presented) .
UR - https://idsa.confex.com/idsa/2016/webprogram/Paper59621.html
UR - https://www.mendeley.com/catalogue/10175f1d-3e00-3bee-828f-249b58061ab1/
U2 - 10.1093/ofid/ofw172.727
DO - 10.1093/ofid/ofw172.727
M3 - Article
VL - 3
JO - Open Forum Infectious Diseases
JF - Open Forum Infectious Diseases
IS - suppl_1
ER -