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Evaluation of intraocular pharmacokinetics and toxicity of prinomastat (AG3340) in the rabbit

  • Lingyun Cheng
  • , Maria E. Rivero
  • , Claudio R. Garcia
  • , Charles D. McDermott
  • , Kelly S. Keefe
  • , Clayton A. Wiley
  • , Kelly A. Soules
  • , Germaine Bergeron-Lynn
  • , Sylvia Vekich
  • , Kanyin Zhang
  • , Krzysztof Appelt
  • , William R. Freeman

Research output: Contribution to journalArticlepeer-review

Original languageEnglish
Pages (from-to)295-304
Number of pages10
JournalJournal of Ocular Pharmacology and Therapeutics
Volume17
Issue number3
DOIs
StatePublished - Jun 2001
Externally publishedYes

ASJC Scopus Subject Areas

  • Ophthalmology
  • Pharmacology
  • Pharmacology (medical)

Keywords

  • Rabbits
  • Gas Chromatography-Mass Spectrometry
  • Organic Chemicals
  • Intraocular Pressure/drug effects
  • Chromatography, High Pressure Liquid
  • Retina/drug effects
  • Animals
  • Antineoplastic Agents/pharmacokinetics
  • Electroretinography/drug effects
  • Vitreous Body/drug effects
  • Angiogenesis Inhibitors/pharmacokinetics
  • Tonometry, Ocular
  • Drug Evaluation, Preclinical
  • Metalloendopeptidases/antagonists & inhibitors

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