@article{6a0085fbc0c348a6bf447baacc9d03eb,
title = "Erythropoietin Inhibits HIF-1α Expression via Upregulation of PHD-2 Transcription and Translation in an In Vitro Model of Hypoxia-Ischemia",
keywords = "EPO, HIF-1α, OGD, PHD-2",
author = "Rhonda Souvenir and Flores, \{Jerry J.\} and Ostrowski, \{Robert P.\} and Anatol Manaenko and Kamil Duris and Jiping Tang",
note = "Hypoxia inducible factor (HIF)-1α is the central transcriptional factor for the regulation of oxygen-associated genes in response to hypoxia. Erythropoietin (EPO), a hematopoietic growth factor, increases oxygen availability during hypoxia/ischemia and is associated with neuroprotection following hypoxia-ischemia in laboratory models of stroke. However, EPO has failed to translate in a clinical setting.",
year = "2014",
month = feb,
doi = "10.1007/s12975-013-0312-z",
language = "English",
volume = "5",
pages = "118--127",
journal = "Translational Stroke Research",
issn = "1868-4483",
number = "1",
}