Ergosterol peroxide suppresses influenza A virus-induced pro-inflammatory response and apoptosis by blocking RIG-I signaling

Beixian Zhou; Xiaoli Liang; Qitong Feng; Jing Li; Xiping Pan; Peifang Xie; Zhihong Jiang; Zifeng Yang

doi:10.1016/j.ejphar.2019.172543

Ergosterol peroxide suppresses influenza A virus-induced pro-inflammatory response and apoptosis by blocking RIG-I signaling

Beixian Zhou
, Xiaoli Liang
, Qitong Feng
, Jing Li
, Xiping Pan
, Peifang Xie
, Zhihong Jiang
, Zifeng Yang

Research output: Contribution to journal › Article › peer-review

Original language	English
Article number	172543
Journal	European Journal of Pharmacology
Volume	860
DOIs	https://doi.org/10.1016/j.ejphar.2019.172543
State	Published - Oct 5 2019
Externally published	Yes

ASJC Scopus Subject Areas

Pharmacology

Keywords

233185)
Anti-inflammatory
Baphicacanthus cusia root
Ergosterol peroxide (PubChem CID
IFN-β
Influenza A virus
RIG-I
A549 Cells
Inflammation Mediators/metabolism
DEAD Box Protein 58/metabolism
Humans
Apoptosis/drug effects
Signal Transduction/drug effects
Interferons/biosynthesis
Animals
Ergosterol/analogs & derivatives
Dogs
Madin Darby Canine Kidney Cells
Influenza A Virus, H1N1 Subtype/physiology
Receptors, Immunologic
Gene Expression Regulation/drug effects
Inflammation/pathology

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10.1016/j.ejphar.2019.172543

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title = "Ergosterol peroxide suppresses influenza A virus-induced pro-inflammatory response and apoptosis by blocking RIG-I signaling",

keywords = "233185), Anti-inflammatory, Baphicacanthus cusia root, Ergosterol peroxide (PubChem CID, IFN-β, Influenza A virus, RIG-I, A549 Cells, Inflammation Mediators/metabolism, DEAD Box Protein 58/metabolism, Humans, Apoptosis/drug effects, Signal Transduction/drug effects, Interferons/biosynthesis, Animals, Ergosterol/analogs \& derivatives, Dogs, Madin Darby Canine Kidney Cells, Influenza A Virus, H1N1 Subtype/physiology, Receptors, Immunologic, Gene Expression Regulation/drug effects, Inflammation/pathology",

author = "Beixian Zhou and Xiaoli Liang and Qitong Feng and Jing Li and Xiping Pan and Peifang Xie and Zhihong Jiang and Zifeng Yang",

year = "2019",

month = oct,

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doi = "10.1016/j.ejphar.2019.172543",

language = "English",

volume = "860",

journal = "European Journal of Pharmacology",

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}

TY - JOUR

T1 - Ergosterol peroxide suppresses influenza A virus-induced pro-inflammatory response and apoptosis by blocking RIG-I signaling

AU - Zhou, Beixian

AU - Liang, Xiaoli

AU - Feng, Qitong

AU - Li, Jing

AU - Pan, Xiping

AU - Xie, Peifang

AU - Jiang, Zhihong

AU - Yang, Zifeng

PY - 2019/10/5

Y1 - 2019/10/5

KW - 233185)

KW - Anti-inflammatory

KW - Baphicacanthus cusia root

KW - Ergosterol peroxide (PubChem CID

KW - IFN-β

KW - Influenza A virus

KW - RIG-I

KW - A549 Cells

KW - Inflammation Mediators/metabolism

KW - DEAD Box Protein 58/metabolism

KW - Humans

KW - Apoptosis/drug effects

KW - Signal Transduction/drug effects

KW - Interferons/biosynthesis

KW - Animals

KW - Ergosterol/analogs & derivatives

KW - Dogs

KW - Madin Darby Canine Kidney Cells

KW - Influenza A Virus, H1N1 Subtype/physiology

KW - Receptors, Immunologic

KW - Gene Expression Regulation/drug effects

KW - Inflammation/pathology

UR - https://www.scopus.com/pages/publications/85069964905

UR - https://www.scopus.com/pages/publications/85069964905#tab=citedBy

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DO - 10.1016/j.ejphar.2019.172543

M3 - Article

C2 - 31323223

AN - SCOPUS:85069964905

SN - 0014-2999

VL - 860

JO - European Journal of Pharmacology

JF - European Journal of Pharmacology

M1 - 172543

ER -

Ergosterol peroxide suppresses influenza A virus-induced pro-inflammatory response and apoptosis by blocking RIG-I signaling

ASJC Scopus Subject Areas

Keywords

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