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Enhanced therapeutic effect of HSV-tk+GCV gene therapy and ionizing radiation for prostate cancer

  • Madhu Chhikara
  • , Hanxian Huang
  • , Maria T. Vlachaki
  • , Xiaohong Zhu
  • , Bin Teh
  • , Kam J. Chiu
  • , Shiao Woo
  • , Barry Berner
  • , E. O.Brian Smith
  • , Kerby C. Oberg
  • , Laura K. Aguilar
  • , Timothy C. Thompson
  • , E. Brian Butler
  • , Estuardo Aguilar-Cordova

Research output: Contribution to journal › Article › peer-review

Original languageEnglish
Pages (from-to)536-542
Number of pages7
JournalMolecular Therapy
Volume3
Issue number4
DOIs
StatePublished - Apr 2001

ASJC Scopus Subject Areas

  • Molecular Medicine
  • Molecular Biology
  • Genetics
  • Pharmacology
  • Drug Discovery

Keywords

  • Adenoviral vector
  • Gene therapy
  • Herpes simplex virus thymidine kinase
  • Prostate cancer
  • Radiotherapy
  • CD4-Positive T-Lymphocytes/metabolism
  • Genetic Therapy/methods
  • Lung Neoplasms/pathology
  • Mice, Inbred C57BL
  • Male
  • Treatment Outcome
  • Combined Modality Therapy
  • Simplexvirus/genetics
  • Neoplasm Metastasis
  • Animals
  • Time Factors
  • Adenoviridae/genetics
  • Antiviral Agents/therapeutic use
  • Prostatic Neoplasms/drug therapy
  • Mice
  • Tumor Cells, Cultured
  • Ganciclovir/therapeutic use

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