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Endogenous Akt Activity Promotes Virus Entry and Predicts Efficacy of Novel Chimeric Orthopoxvirus in Triple-Negative Breast Cancer

  • Audrey H. Choi
  • , Michael P. O'Leary
  • , Jianming Lu
  • , Sang In Kim
  • , Yuman Fong
  • , Nanhai G. Chen

Research output: Contribution to journalArticlepeer-review

Original languageEnglish
Pages (from-to)22-29
Number of pages8
JournalMolecular Therapy - Oncolytics
Volume9
DOIs
StatePublished - Jun 29 2018
Externally publishedYes

ASJC Scopus Subject Areas

  • Molecular Medicine
  • Oncology
  • Cancer Research
  • Pharmacology (medical)

Keywords

  • PI3K/Akt signaling pathway
  • breast cancer
  • chimeric orthopoxvirus
  • immunotherapy
  • oncolytic virus
  • triple negative breast cancer
  • vaccinia virus

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