Effects of Spaceflight on Structural and Material Strength of Growing Bone

Dan M. Spengler; Emily R. Morey; Dennis R. Carter; Russell T. Turner; David J. Baylink

doi:10.3181/00379727-174-41729

Effects of Spaceflight on Structural and Material Strength of Growing Bone

Dan M. Spengler
, Emily R. Morey
, Dennis R. Carter
, Russell T. Turner
, David J. Baylink

Research output: Contribution to journal › Article › peer-review

Abstract

Rats in space for 18.5 days did not exhibit the normal gain in femoral bone strength of terrestrial controls. The strength deficit may have been caused by multiple factors including a diminished bone formation and an inhibition of the gain in tissue material strength. Centrifugation at 1g in space substantially enhanced bone strength, possibly by promoting more normal tissue maturation. Full recovery of bone strength was achieved 25 days after reentry.

Original language	English
Pages (from-to)	224-228
Number of pages	5
Journal	Proceedings of the Society for Experimental Biology and Medicine
Volume	174
Issue number	2
DOIs	https://doi.org/10.3181/00379727-174-41729
State	Published - Nov 1983

ASJC Scopus Subject Areas

General Biochemistry,Genetics and Molecular Biology

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title = "Effects of Spaceflight on Structural and Material Strength of Growing Bone",

abstract = "Rats in space for 18.5 days did not exhibit the normal gain in femoral bone strength of terrestrial controls. The strength deficit may have been caused by multiple factors including a diminished bone formation and an inhibition of the gain in tissue material strength. Centrifugation at 1g in space substantially enhanced bone strength, possibly by promoting more normal tissue maturation. Full recovery of bone strength was achieved 25 days after reentry.",

author = "Spengler, \{Dan M.\} and Morey, \{Emily R.\} and Carter, \{Dennis R.\} and Turner, \{Russell T.\} and Baylink, \{David J.\}",

note = "AbstractRats in space for 18.5 days did not exhibit the normal gain in femoral bone strength of terrestrial controls. The strength deficit may have been caused by multiple factors including a dimin...",

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AU - Spengler, Dan M.

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AU - Baylink, David J.

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AB - Rats in space for 18.5 days did not exhibit the normal gain in femoral bone strength of terrestrial controls. The strength deficit may have been caused by multiple factors including a diminished bone formation and an inhibition of the gain in tissue material strength. Centrifugation at 1g in space substantially enhanced bone strength, possibly by promoting more normal tissue maturation. Full recovery of bone strength was achieved 25 days after reentry.

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Effects of Spaceflight on Structural and Material Strength of Growing Bone

Abstract

ASJC Scopus Subject Areas

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