TY - JOUR
T1 - Effects of sealing the perforated sinus membrane with a resorbable collagen membrane
T2 - a pilot study in humans
AU - Proussaefs, Periklis T.
AU - Lozada, Jaime
AU - Kim, Jay
N1 - EFFECTS OF SEALING THE PERFORATED SINUSMEMBRANE WITH A RESORBABLE COLLAGENMEMBRANE: A PILOT STUDY IN HUMANSCLINICALPeriklis Proussaefs, DDS, MSJaime Lozada, DDSJay Kim, PhDKEY WORDSResorbable collagen membraneSealing perforated sinus membranePeriklis Proussaefs, DDS, MS, is anassistant professor in the Graduate Program inImplant Dentistry, Loma Linda University,Loma Linda, CA 92350, and has a privatepractice
PY - 2003/10/1
Y1 - 2003/10/1
N2 - The effects of repairing the perforated sinus membrane with collagen membrane are unknown. The purpose of this pilot study was to clinically, histologically, and histomorphometrically evaluate the results of repairing the perforated sinus membrane with resorbable collagen membrane. A split-mouth design was followed in the current study. Five subjects requiring bilateral sinus grafting were included in the study, where one site was accidentally perforated during sinus augmentation procedures and the other site was not perforated. The perforated sites were repaired with a resorbable collagen membrane. Dental implants were placed at a second stage and biopsies were harvested from both sinuses. New bone formation was measured for all sites. Implant survival was recorded at second-stage surgery. Nonperforated sites demonstrated significantly more bone formation (34.40%) than perforated sites (12.80%) (P = .016). Implant survival at second-stage surgery was significantly inferior in perforated sites (54.5%) when compared with nonperforated sites (100%) (P = .0146). The study demonstrated that perforation and repair of the Schneiderian membrane can compromise new bone formation and implant survival rate.
AB - The effects of repairing the perforated sinus membrane with collagen membrane are unknown. The purpose of this pilot study was to clinically, histologically, and histomorphometrically evaluate the results of repairing the perforated sinus membrane with resorbable collagen membrane. A split-mouth design was followed in the current study. Five subjects requiring bilateral sinus grafting were included in the study, where one site was accidentally perforated during sinus augmentation procedures and the other site was not perforated. The perforated sites were repaired with a resorbable collagen membrane. Dental implants were placed at a second stage and biopsies were harvested from both sinuses. New bone formation was measured for all sites. Implant survival was recorded at second-stage surgery. Nonperforated sites demonstrated significantly more bone formation (34.40%) than perforated sites (12.80%) (P = .016). Implant survival at second-stage surgery was significantly inferior in perforated sites (54.5%) when compared with nonperforated sites (100%) (P = .0146). The study demonstrated that perforation and repair of the Schneiderian membrane can compromise new bone formation and implant survival rate.
KW - Osteogenesis/physiology
KW - Minerals/therapeutic use
KW - Humans
KW - Middle Aged
KW - Membranes, Artificial
KW - Male
KW - Maxilla/pathology
KW - Maxillary Sinus/injuries
KW - Mucous Membrane/injuries
KW - Alveolar Ridge Augmentation/adverse effects
KW - Absorbable Implants
KW - Pilot Projects
KW - Collagen/therapeutic use
KW - Survival Analysis
KW - Bone Matrix/transplantation
KW - Female
KW - Aged
KW - Dental Implants
KW - Osseointegration/physiology
KW - Bone Substitutes/therapeutic use
UR - https://meridian.allenpress.com/joi/article/29/5/235/1901/Effects-of-Sealing-the-Perforated-Sinus-Membrane
U2 - 10.1563/1548-1336(2003)029<0235:EOSTPS>2.3.CO;2
DO - 10.1563/1548-1336(2003)029<0235:EOSTPS>2.3.CO;2
M3 - Article
C2 - 14620686
VL - 29
SP - 235
EP - 241
JO - Journal of Oral Implantology
JF - Journal of Oral Implantology
IS - 5
ER -