Effective control of large deletions after double-strand breaks by homology-directed repair and dsODN insertion

  • Wei Wen
  • , Zi Jun Quan
  • , Si Ang Li
  • , Zhi Xue Yang
  • , Ya Wen Fu
  • , Feng Zhang
  • , Guo Hua Li
  • , Mei Zhao
  • , Meng Di Yin
  • , Jing Xu
  • , Jian Ping Zhang
  • , Tao Cheng
  • , Xiao Bing Zhang

Research output: Contribution to journalArticlepeer-review

Original languageEnglish
Article number236
JournalGenome Biology
Volume22
Issue number1
DOIs
StatePublished - Dec 2021

ASJC Scopus Subject Areas

  • Ecology, Evolution, Behavior and Systematics
  • Genetics
  • Cell Biology

Keywords

  • CRISPR-Cas9
  • Genome editing
  • Hematopoietic stem and progenitor cells (HSPCs)
  • Homology-directed repair (HDR)
  • Induced pluripotent stem cells (iPSCs)
  • Large fragment deletions
  • Nanopore sequencing
  • Non-homologous end joining (NHEJ)
  • T cells

Cite this