TY - CONF
T1 - E-031 Mri selected elvo patients show favorable response to therapy at extended time from last seen well
AU - Cristiano, B
AU - Cicilioni, K
AU - Pond, M
AU - Lee, J.
AU - Promod, P
AU - Oyoyo, Udochukwu E.
AU - Jacobson, J
N1 - Background Presently accepted criteria for ELVO intervention rely on time from last seen well (LSW) following conformation of LVO diagnosis and favorable baseline imaging. Many patients however present outside established treatment windows or with unknown LSW, and thus, represent a population of great relevance.
PY - 2017/7/1
Y1 - 2017/7/1
N2 - Background Presently accepted criteria for ELVO intervention rely on time from last seen well (LSW) following conformation of LVO diagnosis and favorable baseline imaging. Many patients however present outside established treatment windows or with unknown LSW, and thus, represent a population of great relevance. Here we present in hospital and 90 day outcomes of a large patient cohort, many treated at extended LSW, after MRI assessment. Population ELVO patients with isolated occlusion of the carotid terminus or M1 segment, baseline mRS 18, and no MRI contraindication. Methods Regression analysis with primary outcome 90d mRS 2B recanalization success was 85%. No patient had PH2 intracranial hemorrhage, 1 had PH1, 3 HT1, and 2 SAH, none requiring additional intervention. 90d mRS 2B recanalization. Many patients (20/40) showed early response to therapy as defined by improvement in NIHSS>4, an effect that was more likely with TICI >2B recanalization (OR 2.53 [95CI: 1.663-3.876]), and equally likely with femoral access before or after 6 hours LSW (OR 1.403 [95CI: 0.782-2.516]). The strongest predictor of 90d mRS
AB - Background Presently accepted criteria for ELVO intervention rely on time from last seen well (LSW) following conformation of LVO diagnosis and favorable baseline imaging. Many patients however present outside established treatment windows or with unknown LSW, and thus, represent a population of great relevance. Here we present in hospital and 90 day outcomes of a large patient cohort, many treated at extended LSW, after MRI assessment. Population ELVO patients with isolated occlusion of the carotid terminus or M1 segment, baseline mRS 18, and no MRI contraindication. Methods Regression analysis with primary outcome 90d mRS 2B recanalization success was 85%. No patient had PH2 intracranial hemorrhage, 1 had PH1, 3 HT1, and 2 SAH, none requiring additional intervention. 90d mRS 2B recanalization. Many patients (20/40) showed early response to therapy as defined by improvement in NIHSS>4, an effect that was more likely with TICI >2B recanalization (OR 2.53 [95CI: 1.663-3.876]), and equally likely with femoral access before or after 6 hours LSW (OR 1.403 [95CI: 0.782-2.516]). The strongest predictor of 90d mRS
UR - https://jnis.bmj.com/content/9/Suppl_1/A56.1
UR - https://jnis.bmj.com/content/neurintsurg/9/Suppl_1/A56.1.full.pdf
UR - https://www.mendeley.com/catalogue/a8f0a21a-f8d4-3d8f-bbe3-df3bcd30772c/
U2 - 10.1136/neurintsurg-2017-SNIS.103
DO - 10.1136/neurintsurg-2017-SNIS.103
M3 - Poster
SP - A56
ER -