TY - JOUR
T1 - DNA promoter hypermethylation in saliva for the early diagnosis of oral cancer.
AU - Viet, C. T.
AU - Jordan, Richard C.K.
AU - Schmidt, Brian L.
N1 - Oral health care professionals could drastically improve the quality of life for patients with potentially malignant oral lesions by using a noninvasive test that could be used to detect cancer using saliva. Promoter DNA hypermethylation is a critical step in oral carcinogenesis and has a number of significant advantages over genetic and protein diagnostic markers.
PY - 2007/12
Y1 - 2007/12
N2 - Oral health care professionals could drastically improve the quality of life for patients with potentially malignant oral lesions by using a noninvasive test that could be used to detect cancer using saliva. Promoter DNA hypermethylation is a critical step in oral carcinogenesis and has a number of significant advantages over genetic and protein diagnostic markers. Methylight is a recently developed assay that rapidly quantifies promoter hypermethylation and could potentially be applied into a clinical setting.
AB - Oral health care professionals could drastically improve the quality of life for patients with potentially malignant oral lesions by using a noninvasive test that could be used to detect cancer using saliva. Promoter DNA hypermethylation is a critical step in oral carcinogenesis and has a number of significant advantages over genetic and protein diagnostic markers. Methylight is a recently developed assay that rapidly quantifies promoter hypermethylation and could potentially be applied into a clinical setting.
UR - http://www.scopus.com/inward/record.url?scp=39649109929&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=39649109929&partnerID=8YFLogxK
M3 - Article
C2 - 18240747
SN - 1043-2256
VL - 35
SP - 844
EP - 849
JO - Journal of the California Dental Association
JF - Journal of the California Dental Association
IS - 12
ER -