Dj4 targets the rho-associated protein kinase pathway and attenuates disease progression in preclinical murine models of acute myeloid leukemia

Upendarrao Golla; Melanie A. Ehudin; Charyguly Annageldiyev; Zheng Zeng; Diwakar Bastihalli Tukaramrao; Anna Tarren; Abhijit A. Date; Irina Elcheva; Arthur Berg; Shantu Amin; Thomas P. Loughran; Mark Kester; Dhimant Desai; Sinisa Dovat; David Claxton; Arati Sharma

doi:10.3390/cancers13194889

Dj4 targets the rho-associated protein kinase pathway and attenuates disease progression in preclinical murine models of acute myeloid leukemia

Upendarrao Golla
, Melanie A. Ehudin
, Charyguly Annageldiyev
, Zheng Zeng
, Diwakar Bastihalli Tukaramrao
, Anna Tarren
, Abhijit A. Date
, Irina Elcheva
, Arthur Berg
, Shantu Amin
, Thomas P. Loughran
, Mark Kester
, Dhimant Desai
, Sinisa Dovat
, David Claxton
, Arati Sharma

Research output: Contribution to journal › Article › peer-review

Original language	English
Article number	4889
Journal	Cancers
Volume	13
Issue number	19
DOIs	https://doi.org/10.3390/cancers13194889
State	Published - Oct 1 2021
Externally published	Yes

ASJC Scopus Subject Areas

Oncology
Cancer Research

Keywords

Acute myeloid leukemia
Cell line-derived xenograft
DJ4
Preclinical AML murine model
Primary human AML cells
Rho-associated protein kinase

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10.3390/cancers13194889

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Golla, U., Ehudin, M. A., Annageldiyev, C., Zeng, Z., Bastihalli Tukaramrao, D., Tarren, A., Date, A. A., Elcheva, I., Berg, A., Amin, S., Loughran, T. P., Kester, M., Desai, D., Dovat, S., Claxton, D., & Sharma, A. (2021). Dj4 targets the rho-associated protein kinase pathway and attenuates disease progression in preclinical murine models of acute myeloid leukemia. Cancers, 13(19), Article 4889. https://doi.org/10.3390/cancers13194889

Golla, U, Ehudin, MA, Annageldiyev, C, Zeng, Z, Bastihalli Tukaramrao, D, Tarren, A, Date, AA, Elcheva, I, Berg, A, Amin, S, Loughran, TP, Kester, M, Desai, D, Dovat, S, Claxton, D & Sharma, A 2021, 'Dj4 targets the rho-associated protein kinase pathway and attenuates disease progression in preclinical murine models of acute myeloid leukemia', Cancers, vol. 13, no. 19, 4889. https://doi.org/10.3390/cancers13194889

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keywords = "Acute myeloid leukemia, Cell line-derived xenograft, DJ4, Preclinical AML murine model, Primary human AML cells, Rho-associated protein kinase",

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AU - Golla, Upendarrao

AU - Ehudin, Melanie A.

AU - Annageldiyev, Charyguly

AU - Zeng, Zheng

AU - Bastihalli Tukaramrao, Diwakar

AU - Tarren, Anna

AU - Date, Abhijit A.

AU - Elcheva, Irina

AU - Berg, Arthur

AU - Amin, Shantu

AU - Loughran, Thomas P.

AU - Kester, Mark

AU - Desai, Dhimant

AU - Dovat, Sinisa

AU - Claxton, David

AU - Sharma, Arati

PY - 2021/10/1

Y1 - 2021/10/1

KW - Acute myeloid leukemia

KW - Cell line-derived xenograft

KW - DJ4

KW - Preclinical AML murine model

KW - Primary human AML cells

KW - Rho-associated protein kinase

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DO - 10.3390/cancers13194889

M3 - Article

AN - SCOPUS:85115977992

SN - 2072-6694

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JO - Cancers

JF - Cancers

IS - 19

M1 - 4889

ER -

Dj4 targets the rho-associated protein kinase pathway and attenuates disease progression in preclinical murine models of acute myeloid leukemia

ASJC Scopus Subject Areas

Keywords

Access to Document

OpenUrl availability

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