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Discovery of NFκB2-Coordinated Dual Regulation of Mitochondrial and Nuclear Genomes Leads to an Effective Therapy for Acute Myeloid Leukemia

Research output: Contribution to journalArticlepeer-review

Original languageEnglish
Article number8532
JournalInternational Journal of Molecular Sciences
Volume25
Issue number15
DOIs
StatePublished - Aug 2024

ASJC Scopus Subject Areas

  • Catalysis
  • Molecular Biology
  • Spectroscopy
  • Computer Science Applications
  • Physical and Theoretical Chemistry
  • Organic Chemistry
  • Inorganic Chemistry

Keywords

  • AML
  • ATP
  • FLT3
  • NFκB2
  • NRF1
  • TFAM
  • gilteritinib
  • metabolism
  • mitochondrion
  • Promoter Regions, Genetic
  • Cell Nucleus/metabolism
  • Mitochondria/metabolism
  • Humans
  • Transcription Factors/genetics
  • Gene Expression Regulation, Leukemic
  • DNA-Binding Proteins/genetics
  • Cell Line, Tumor
  • Mitochondrial Proteins/genetics
  • Genome, Mitochondrial
  • Leukemia, Myeloid, Acute/genetics

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