Discovery of molecular mechanisms of traditional Chinese medicinal formula Si-Wu-Tang using gene expression Microarray and Connectivity Map

  • Zhining Wen
  • , Zhijun Wang
  • , Steven Wang
  • , Ranadheer Ravula
  • , Lun Yang
  • , Jun Xu
  • , Charles Wang
  • , Zhong Zuo
  • , Moses S.S. Chow
  • , Leming Shi
  • , Ying Huang

Research output: Contribution to journalArticlepeer-review

Original languageEnglish
Article numbere18278
JournalPLoS ONE
Volume6
Issue number3
DOIs
StatePublished - Mar 28 2011
Externally publishedYes

ASJC Scopus Subject Areas

  • General

Keywords

  • Drugs, Chinese Herbal/pharmacology
  • Estradiol/pharmacology
  • Reproducibility of Results
  • Medicine, Chinese Traditional
  • Humans
  • Databases, Genetic
  • Enzyme Assays
  • Gene Expression Profiling
  • Response Elements/genetics
  • Reverse Transcriptase Polymerase Chain Reaction
  • Dose-Response Relationship, Drug
  • Genes, Reporter/genetics
  • Oligonucleotide Array Sequence Analysis/methods
  • Oxidative Stress/drug effects
  • Reference Standards
  • Antioxidants/metabolism
  • Luciferases/metabolism
  • Cell Line, Tumor
  • Software
  • NF-E2-Related Factor 2/genetics
  • Gene Expression Regulation/drug effects
  • Cluster Analysis

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