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Deletion of the N-terminus of murine MAP2 by gene targeting disrupts hippocampal CA1 neuron architecture and alters contextual memory

  • Z. Khuchua
  • , D. F. Wozniak
  • , M. E. Bardgett
  • , Z. Yue
  • , M. McDonald
  • , J. Boero
  • , R. E. Hartman
  • , H. Sims
  • , A. W. Strauss

Research output: Contribution to journalArticlepeer-review

Original languageEnglish
Pages (from-to)101-111
Number of pages11
JournalNeuroscience
Volume119
Issue number1
DOIs
StatePublished - Jun 18 2003
Externally publishedYes

ASJC Scopus Subject Areas

  • General Neuroscience

Keywords

  • CAMP
  • Cytoskeleton
  • Hippocampus
  • PKA
  • Signal transduction
  • Immunohistochemistry
  • Hippocampus/cytology
  • Peptide Fragments
  • Phosphorylation
  • Cyclic AMP/pharmacology
  • Tubulin/metabolism
  • Male
  • Reaction Time
  • Motor Activity
  • Microtubule-Associated Proteins/genetics
  • Behavior, Animal
  • Stem Cells
  • RNA, Messenger/biosynthesis
  • Gene Deletion
  • Memory/physiology
  • Female
  • Electric Stimulation/adverse effects
  • Conditioning, Psychological
  • Cues
  • Amino Acid Sequence
  • Gene Targeting
  • Phosphorus Isotopes
  • Acoustic Stimulation
  • Mice, Inbred C57BL
  • Paclitaxel/pharmacology
  • Adenosine Triphosphate/metabolism
  • Mice, Transgenic
  • Neurons/cytology
  • Reverse Transcriptase Polymerase Chain Reaction
  • Blotting, Western
  • Fear
  • Homozygote
  • Animals
  • Angiogenesis Inhibitors/pharmacology
  • Heterozygote
  • Mice

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