Contact Dermatitis in the Patient with Atopic Dermatitis

Emily C. Milam, Sharon E. Jacob, David E. Cohen

Research output: Contribution to journalArticlepeer-review

Abstract

Atopic dermatitis (AD) and allergic contact dermatitis (ACD) are common T-cell-mediated inflammatory skin conditions that can share clinical presentations. The variable expression of ACD among patients with AD represents the shades of gray of the multifaceted relationship between the 2 disorders, where increased allergen permeation in compromised epidermal barriers augments antigen presentation and sensitization, with subsequent immune dysregulation. Further studies are needed to define the relationship and immunologic intersection points of these 2 conditions.

Original languageEnglish
Pages (from-to)18-26
Number of pages9
JournalJournal of Allergy and Clinical Immunology: In Practice
Volume7
Issue number1
DOIs
StatePublished - Jan 2019

ASJC Scopus Subject Areas

  • Immunology and Allergy

Keywords

  • Allergic contact dermatitis
  • Atopic dermatitis
  • Atopy
  • Contact allergen
  • Immunology
  • Patch testing

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