Abstract
Atopic dermatitis (AD) and allergic contact dermatitis (ACD) are common T-cell-mediated inflammatory skin conditions that can share clinical presentations. The variable expression of ACD among patients with AD represents the shades of gray of the multifaceted relationship between the 2 disorders, where increased allergen permeation in compromised epidermal barriers augments antigen presentation and sensitization, with subsequent immune dysregulation. Further studies are needed to define the relationship and immunologic intersection points of these 2 conditions.
Original language | English |
---|---|
Pages (from-to) | 18-26 |
Number of pages | 9 |
Journal | Journal of Allergy and Clinical Immunology: In Practice |
Volume | 7 |
Issue number | 1 |
DOIs | |
State | Published - Jan 2019 |
ASJC Scopus Subject Areas
- Immunology and Allergy
Keywords
- Allergic contact dermatitis
- Atopic dermatitis
- Atopy
- Contact allergen
- Immunology
- Patch testing