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Conditional disruption of IGF-I gene in type 1α collagen-expressing cells shows an essential role of IGF-I in skeletal anabolic response to loading

Research output: Contribution to journalArticlepeer-review

Original languageEnglish
Pages (from-to)E1191-E1197
JournalAmerican Journal of Physiology - Endocrinology and Metabolism
Volume301
Issue number6
DOIs
StatePublished - Dec 2011

ASJC Scopus Subject Areas

  • General Medicine

Keywords

  • Gene expression
  • Insulin-like growth factor I
  • Mechanical loading
  • Micro-computed tomography
  • Osteoid
  • Collagen Type I/genetics
  • Gene Transfer Techniques
  • Bone Density
  • Mice, Inbred C57BL
  • Stress, Mechanical
  • Gene Expression Profiling
  • Insulin-Like Growth Factor I/genetics
  • Mice, Knockout
  • Metabolism/genetics
  • Osteoblasts/cytology
  • Animals
  • Gene Deletion
  • Weight-Bearing/physiology
  • Bone and Bones/cytology
  • Female
  • Mice
  • Organ Specificity/genetics
  • Collagen Type I, alpha 1 Chain

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