Computer-simulated biopsy marking system for endoscopic surveillance of gastric lesions: A pilot study

Weiling Hu, Bin Wang, Leimin Sun, Shujie Chen, Liangjing Wang, Kan Wang, Jiaguo Wu, John J. Kim, Jiquan Liu, Ning Dai, Huilong Duan, Jianmin Si

Research output: Contribution to journalArticlepeer-review

Abstract

Endoscopic tattoo with India ink injection for surveillance of premalignant gastric lesions is technically cumbersome and may not be durable. The aim of the study is to evaluate the accuracy of a novel, computer-simulated biopsy marking system (CSBMS) developed for the endoscopic marking of gastric lesions. Twenty-five patients with history of gastric intestinal metaplasia received both CSBMS-guided marking and India ink injection in five points in the stomach at index endoscopy. A second endoscopy was performed at three months. Primary outcome was accuracy of CSBMS (distance between CSBMS probe-guided site and tattoo site measured by CSBMS). The mean accuracy of CSBMS at angularis was 5.3 ± 2.2 mm, antral lesser curvature 5.7 ± 1.4 mm, antral greater curvature 6.1 ± 1.1 mm, antral anterior wall 6.9 ± 1.6 mm, and antral posterior wall 6.9 ± 1.6 mm. CSBMS (2.3 ± 0.9 versus 12.5 ± 4.6 seconds; P = 0.02) required less procedure time compared to endoscopic tattooing. No adverse events were encountered. CSBMS accurately identified previously marked gastric sites by endoscopic tattooing within 1 cm on follow-up endoscopy.

Original languageEnglish
Article number197270
JournalBioMed Research International
Volume2015
DOIs
StatePublished - 2015

ASJC Scopus Subject Areas

  • General Biochemistry,Genetics and Molecular Biology
  • General Immunology and Microbiology

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