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Chronically Radiation-Exposed Survivor Glioblastoma Cells Display Poor Response to Chk1 Inhibition under Hypoxia

  • Nareg Pinarbasi-Degirmenci
  • , Ilknur Sur-Erdem
  • , Vuslat Akcay
  • , Yasemin Bolukbasi
  • , Ugur Selek
  • , Ihsan Solaroglu
  • , Tugba Bagci-Onder

Research output: Contribution to journalArticlepeer-review

Original languageEnglish
Article number7051
JournalInternational Journal of Molecular Sciences
Volume23
Issue number13
DOIs
StatePublished - Jul 1 2022

ASJC Scopus Subject Areas

  • Catalysis
  • Molecular Biology
  • Spectroscopy
  • Computer Science Applications
  • Physical and Theoretical Chemistry
  • Organic Chemistry
  • Inorganic Chemistry

Keywords

  • Chk1
  • DNA damage response
  • glioblastoma
  • hypoxia
  • radioresistance
  • radiotherapy
  • Humans
  • Survivors
  • Cell Cycle Proteins/metabolism
  • Checkpoint Kinase 1/genetics
  • Glioblastoma/genetics
  • Radiation Tolerance/genetics
  • Cell Line, Tumor
  • Hypoxia
  • DNA Damage

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